SCHEMBL8434167

SCHEMBL8434167

COc1cc2ccc1OCCC2=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 4/20 0.47
MAPT P10636 3/20 0.44
LMNA P02545 2/20 0.44
CYP19A1 P11511 3/20 0.42
MAOA P21397 1/20 0.39
MAOB P27338 1/20 0.39
MET P08581 1/20 0.38
ALDH1A1 P00352 2/20 0.37
TSHR P16473 2/20 0.37
HSP90AA1 P07900 1/20 0.37
HSP90AB1 P08238 1/20 0.37
KDM4E B2RXH2 2/20 0.37
ATM Q13315 1/20 0.37
GRM5 P41594 1/20 0.37
PDE4A P27815 1/20 0.37
PDE4B Q07343 1/20 0.37
PDE4C Q08493 1/20 0.37
PDE4D Q08499 1/20 0.37
PDE3B Q13370 1/20 0.37
PDE3A Q14432 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12316567 0.72 KDM4E (0.51) MAPTLMNAMAOAMAOBALDH1A1
SCHEMBL31411168 0.70 MAPT (0.51) MAPTLMNACYP19A1MAOBALDH1A1
SCHEMBL12316566 0.70 MAPT (0.51) MAPTLMNACYP19A1MAOBALDH1A1
SCHEMBL769313 0.70 NPC1 (0.54) MAPTCYP19A1MAOAMAOBALDH1A1
SCHEMBL6483294 0.69 CYP19A1 (0.44) MAPTLMNACYP19A1ALDH1A1TSHR
SCHEMBL5473517 0.69 MAOB (0.53) CYP19A1MAOAMAOBALDH1A1GRM5
SCHEMBL23363326 0.69 MAOB (0.45) MAPTLMNAMAOAMAOBALDH1A1
SCHEMBL16333691 0.69 MAOB (0.45) MAPTLMNAMAOAMAOBALDH1A1
SCHEMBL16264018 0.69 KDM4E (0.54) MAPTLMNAALDH1A1KDM4EATM
SCHEMBL12316574 0.69 ALDH1A1 (0.49) MAPTLMNAMAOBALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5900416-A COSOLUBILIZING AGENT SELECTED FROM NIACINAMIDE, NICOTINIC ACID AND MIXTURES ANTHEA ENTERPRISES INCORPORATED (US) 1999-05-04 US claimed
WO-1997027750-A1 AQUEOUS CAFFEINE DOSAGE FORMS ANTHEA ENTERPRISES INCORPORATED (US) 1997-08-07 WO claimed
US-20140323505-A1 ORAL RINSE COMPOSITION AND METHOD TO DELIVER ENERGY SUPPLEMENTS Rinsenergy LLC (US) 2014-10-30 US disclosed
WO-2014176449-A1 ORAL RINSE COMPOSITION AND METHOD TO DELIVER ENERGY SUPPLEMENTS Rinsenergy LLC (US) 2014-10-30 WO disclosed
US-5900416-A COSOLUBILIZING AGENT SELECTED FROM NIACINAMIDE, NICOTINIC ACID AND MIXTURES ANTHEA ENTERPRISES INCORPORATED (US) 1999-05-04 US disclosed
WO-1997027750-A1 AQUEOUS CAFFEINE DOSAGE FORMS ANTHEA ENTERPRISES INCORPORATED (US) 1997-08-07 WO disclosed