SCHEMBL6483294

SCHEMBL6483294

COc1cc2ccc1OOC2=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 3/20 0.44
PDE4A P27815 2/20 0.41
ALDH1A1 P00352 5/20 0.41
CYP3A4 P08684 3/20 0.41
HSD17B10 Q99714 2/20 0.41
TSHR P16473 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
KDM4E B2RXH2 4/20 0.40
HPGD P15428 4/20 0.40
MAPT P10636 3/20 0.40
THRB P10828 2/20 0.40
MEN1 O00255 2/20 0.40
MAPK1 P28482 2/20 0.40
KMT2A Q03164 2/20 0.40
GLA P06280 1/20 0.40
ABCB1 P08183 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
ABCG2 Q9UNQ0 1/20 0.39
PTPRC P08575 1/20 0.39
PTPN1 P18031 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8434167 0.69 ERN1 (0.47) CYP19A1PDE4AALDH1A1HSD17B10TSHR
SCHEMBL8840880 0.63 PDE4A (0.67) PDE4AALDH1A1CYP3A4HSD17B10TSHR
SCHEMBL4302847 0.63 DYRK1A (0.65) PDE4AALDH1A1CYP3A4HSD17B10TSHR
SCHEMBL29385001 0.63 KDM4E (0.55) CYP19A1PDE4AALDH1A1TSHRKDM4E
SCHEMBL3125629 0.62 PDE4A (0.72) PDE4AALDH1A1CYP3A4HSD17B10KDM4E
SCHEMBL16541896 0.61 PDE4A (0.57) PDE4AALDH1A1CYP3A4HSD17B10TSHR
SCHEMBL23426278 0.61 CTRC (0.42) ALDH1A1CYP3A4HSD17B10TDP1MAPT
SCHEMBL10425842 0.60 TSHR (0.66) ALDH1A1TSHRKDM4ESMN1; SMN2PKM
SCHEMBL457121 0.60 DYRK1A (0.56) ALDH1A1CYP3A4HSD17B10TSHRTDP1
SCHEMBL4533772 0.60 L3MBTL1 (0.62) PDE4AALDH1A1HSD17B10TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030055066-A1 Phenoxypropanol connected with phenylpiperazine and phenoxyalkylamine terminal in its side chain LIN, TONG-HO (TW) 2003-03-20 US claimed
US-20230416449-A1 AROMATIC DIOL COMPOUNDS, DIEPOXIDE COMPOUNDS, POLYMERS PREPARED FROM SUCH COMPOUNDS, AND METHODS FOR MAKING THE SAME SWIMC LLC (US) 2023-12-28 US disclosed
EP-4244150-A1 AROMATIC DIOL COMPOUNDS, DIEPOXIDE COMPOUNDS, POLYMERS PREPARED FROM SUCH COMPOUNDS, AND METHODS FOR MAKING THE SAME Swimc LLC (US) 2023-09-20 EP disclosed
CN-116438120-A Aromatic diol compound, diepoxide compound, polymer prepared from such compound, and process for producing the same SWIMC有限公司 2023-07-14 CN disclosed
WO-2022104222-A1 AROMATIC DIOL COMPOUNDS, DIEPOXIDE COMPOUNDS, POLYMERS PREPARED FROM SUCH COMPOUNDS, AND METHODS FOR MAKING THE SAME SWIMC LLC (US) 2022-05-19 WO disclosed
US-6846826-B2 Phenoxypropanol connected with phenylpiperazine and phenoxyalkylamine terminal in its side chain Chen, Ing-Jun (TW) 2005-01-25 US disclosed
US-20030055066-A1 Phenoxypropanol connected with phenylpiperazine and phenoxyalkylamine terminal in its side chain LIN, TONG-HO (TW) 2003-03-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030055066-A1 Phenoxypropanol connected with phenylpiperazine and phenoxyalkylamine terminal in its side chain KCNH2, ADRB3, KCNH3 CYP19A1 2997/4885PDE4A 2859/4885ALDH1A1 810/4885
US-20230416449-A1 AROMATIC DIOL COMPOUNDS, DIEPOXIDE COMPOUNDS, POLYMERS PREPARED FROM SUCH COMPOUNDS, AND METHODS FOR MAKING THE SAME DDT, EPHX2, AOC1 CYP19A1 405/4885PDE4A 3845/4885ALDH1A1 1015/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.