Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 10/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.58 |
| ▸ | GRM5 | P41594 | 1/20 | 0.54 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.54 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8431815 | 0.88 | MAOB (0.67) | MAOBMAOASCN9AGRM5NR4A2 | |
| SCHEMBL964301 | 0.81 | MAOB (0.80) | MAOBMAOASCN9APARP10 | |
| SCHEMBL8434308 | 0.79 | MAOB (0.64) | MAOBMAOASCN9AGRM5NR4A2 | |
| SCHEMBL9626407 | 0.77 | MAOB (0.69) | MAOBMAOASCN9ANR4A2PARP10 | |
| SCHEMBL965290 | 0.77 | MAOB (0.62) | MAOBMAOASCN9ANR4A2PARP10 | |
| SCHEMBL5035179 | 0.77 | MAOB (0.61) | MAOBMAOASCN9AGRM5NR4A2 | |
| SCHEMBL3976085 | 0.76 | MAOB (0.58) | MAOBMAOASCN9AGRM5NR4A2 | |
| SCHEMBL14323980 | 0.76 | MAOB (0.69) | MAOBMAOASCN9AGRM5NR4A2 | |
| SCHEMBL8935244 | 0.76 | MAOB (0.69) | MAOBMAOASCN9AGRM5NR4A2 | |
| SCHEMBL4425539 | 0.75 | MAOB (0.60) | MAOBMAOASCN9AGRM5NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5945454-A | 2-(4-substituted)-benzylamino-2-methyl-propanamide derivatives | PHARMACIA & UPJOHN, S.P.A. (IT) | 1999-08-31 | — | — | US | disclosed |