SCHEMBL8935244

SCHEMBL8935244

CC(N)C(=O)NCc1ccc(OCc2cccc(F)c2)cc1

nearest known ligand 0.69

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAOB P27338 10/20 0.69
MAOA P21397 2/20 0.69
SCN9A Q15858 1/20 0.69
PARP10 Q53GL7 1/20 0.57
GRM5 P41594 1/20 0.55
PPARA Q07869 1/20 0.55
NR4A2 P43354 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14323980 1.00 MAOB (0.69) MAOBMAOASCN9APARP10GRM5
SCHEMBL994279 0.88 MAOB (0.62) MAOBMAOASCN9APARP10GRM5
SCHEMBL8935332 0.86 GID4 (0.62) MAOBMAOA
Hydrochloric Acid SCHEMBL30001586 0.86 MAOB (0.60) MAOBMAOASCN9APARP10PPARA
SCHEMBL994999 0.85 MAOB (0.65) MAOBMAOASCN9APARP10GRM5
SCHEMBL993071 0.85 MAOB (0.65) MAOBMAOASCN9APARP10GRM5
SCHEMBL993070 0.85 MAOB (0.65) MAOBMAOASCN9APARP10GRM5
SCHEMBL992772 0.84 MAOB (0.60) MAOBMAOASCN9AGRM5PPARA
SCHEMBL8431815 0.82 MAOB (0.67) MAOBMAOASCN9APARP10GRM5
SCHEMBL1534881 0.82 MAOB (0.63) MAOBMAOASCN9APARP10PPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5502079-A TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS FARMITALIA CARLO ERBA S.R.L. (IT) 1996-03-26 US disclosed