Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 3/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8434327 | 0.78 | CTSL (0.40) | ALDH1A1MAPTKDM4EMAPK1L3MBTL1 | |
| SCHEMBL9284657 | 0.78 | MAPT (0.48) | ALDH1A1MAPTKDM4EMAPK1CA12 | |
| SCHEMBL9337494 | 0.74 | MAPT (0.44) | ALDH1A1MAPTKDM4EMAPK1CA12 | |
| SCHEMBL6025125 | 0.73 | ALDH1A1 (0.43) | ALDH1A1MAPTKDM4EMAPK1CA12 | |
| SCHEMBL8037160 | 0.72 | NPC1 (0.54) | ALDH1A1MAPTKDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL9136116 | 0.72 | NPC1 (0.54) | ALDH1A1MAPTKDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL7110405 | 0.72 | NPC1 (0.54) | ALDH1A1MAPTKDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL9065504 | 0.72 | CA12 (0.57) | ALDH1A1MAPTKDM4EMAPK1CA12 | |
| SCHEMBL472165 | 0.72 | CA12 (0.57) | ALDH1A1MAPTKDM4EMAPK1CA12 | |
| SCHEMBL10491975 | 0.71 | CA12 (0.49) | ALDH1A1MAPTKDM4EMAPK1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0475444-B1 | Use of 4-fluoro-pyrimidine derivatives as components for ferroelectric liquid crystal mixtures and process to prepare these compounds | HOECHST AG (DE) | 1999-07-14 | — | — | EP | disclosed |
| EP-0475444-A1 | Use of 4-fluoro-pyrimidine derivatives as components for ferroelectric liquid crystal mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-03-18 | — | — | EP | disclosed |