SCHEMBL843435

SCHEMBL843435

C=CC(=O)OCCOC(=O)/C=C/c1ccccc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1B10 O60218 7/20 0.71
AKR1B1 P15121 7/20 0.71
LMNA P02545 2/20 0.61
THRB P10828 1/20 0.61
MAOB P27338 1/20 0.60
APP P05067 2/20 0.59
MEN1 O00255 2/20 0.57
KMT2A Q03164 2/20 0.57
ALDH1A1 P00352 2/20 0.56
CA12 O43570 2/20 0.53
CA4 P22748 2/20 0.53
CA6 P23280 2/20 0.53
CA5A P35218 2/20 0.53
CA7 P43166 2/20 0.53
CA9 Q16790 2/20 0.53
CA14 Q9ULX7 2/20 0.53
CA5B Q9Y2D0 2/20 0.53
CA1 P00915 1/20 0.53
MET P08581 1/20 0.53
CYP3A4 P08684 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL843436 1.00 AKR1B10 (0.71) AKR1B10AKR1B1LMNATHRBMAOB
SCHEMBL8217319 0.94 AKR1B10 (0.63) AKR1B10AKR1B1LMNATHRBMAOB
SCHEMBL11339149 0.94 AKR1B10 (0.63) AKR1B10AKR1B1LMNATHRBMAOB
SCHEMBL11339150 0.94 AKR1B10 (0.63) AKR1B10AKR1B1LMNATHRBMAOB
SCHEMBL8217316 0.94 AKR1B10 (0.63) AKR1B10AKR1B1LMNATHRBMAOB
SCHEMBL20090792 0.91 CA12 (0.61) AKR1B10AKR1B1LMNATHRBMAOB
SCHEMBL19279512 0.91 AKR1B10 (0.83) AKR1B10AKR1B1LMNAMAOBAPP
SCHEMBL16234738 0.91 AKR1B10 (0.83) AKR1B10AKR1B1LMNAMAOBAPP
SCHEMBL9277968 0.91 AKR1B10 (0.83) AKR1B10AKR1B1LMNAMAOBAPP
SCHEMBL925591 0.87 AKR1B10 (0.68) AKR1B10AKR1B1LMNAMAOBAPP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 158 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3850018-B1 ANTIMICROBIAL CONTACT LENSES KERAMED INC (US) 2023-08-23 EP claimed
CN-114314918-B Oil removal and oil removal process for coal-based needle coke wastewater 华夏碧水环保科技股份有限公司 2023-04-25 CN claimed
CN-114314918-A Oil removal and oil removal process for coal-based needle coke wastewater 华夏碧水环保科技有限公司 2022-04-12 CN claimed
CN-114275974-A Treatment process of needle coke wastewater 华夏碧水环保科技有限公司 2022-04-05 CN claimed
US-20210369607-A1 Antimicrobial Contact Lenses KeraMed, Inc. (US) 2021-12-02 US claimed
EP-3850018-A1 ANTIMICROBIAL CONTACT LENSES Keramed, Inc. (US) 2021-07-21 EP claimed
CN-111836839-A Antimicrobial contact lenses 克拉梅德有限公司 2020-10-27 CN claimed
EP-3639066-A1 CELL GROWTH INHIBITING COPOLYMER FOR USE IN OPHTHALMIC IMPLANTS Shiuey, Yichieh (US) 2020-04-22 EP claimed
CN-110753859-A Cytostatic copolymers for use in ophthalmic implants 伊齐耶·舒埃 2020-02-04 CN claimed
WO-2019194903-A1 ANTIMICROBIAL CONTACT LENSES KeraMed, Inc. (US) 2019-10-10 WO claimed
US-20060121217-A1 Composite material comprising layered hydrophilic coatings MCMASTER UNIVERSITY 2006-06-08 US claimed
WO-2006034575-A1 COMPOSITE MATERIAL COMPRISING LAYERED HYDROPHILIC COATINGS MCMASTER UNIVERSITY (CA) 2006-04-06 WO claimed
WO-2006015495-A1 COMPOSITE MATERIAL COMPRISING A NON-CROSSLINKED GEL POLYMER MCMASTER UNIVERSITY (CA) 2006-02-16 WO claimed
US-20060000778-A1 high-performance membrane designed for the selective removal of a polar fluid (water) from less polar fluids (organic solvents), by a pervaporation using a composite membrane contaiing ultrafiltration membrane as support ( e.g. cellulose acetate) and a crosslinked copolymer of anionic, cationic monomers MCMASTER UNIVERSITY (CA) 2006-01-05 US claimed
WO-2005102503-A1 PERVAPORATION COMPOSITE MEMBRANES MCMASTER UNIVERSITY (CA) 2005-11-03 WO claimed
US-4675252-A Base material having a dyed membrane on the surface thereof, and method for dyeing a membrane thereon NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1987-06-23 US claimed
EP-0179921-A1 BASE MATERIAL HAVING A DYED SURFACE FILM AND DYEING METHOD NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1986-05-07 EP claimed
US-4234674-A Amino-functional photopolymer compositions and photo-oxidation imaging processes employing same MONSANTO COMPANY (US) 1980-11-18 US claimed
US-4188223-A Amino-functional photopolymer compositions and photo-oxidation imaging processes employing same MONSANTO COMPANY (US) 1980-02-12 US claimed
US-3953212-A SILICONE RUBBERS FUJI PHOTO FILM CO., LTD. (JA) 1976-04-27 US claimed