Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8431918 | 0.94 | MAPT (0.34) | MAPTPTGESMEN1KMT2AL3MBTL1 | |
| SCHEMBL7143041 | 0.68 | POLB (0.34) | MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL8547960 | 0.68 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL8551905 | 0.68 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL8692650 | 0.68 | — | — | |
| SCHEMBL8692041 | 0.67 | — | — | |
| SCHEMBL8548197 | 0.66 | HTT (0.32) | L3MBTL1ALDH1A1 | |
| SCHEMBL8548284 | 0.66 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL7140896 | 0.66 | POLB (0.34) | MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL1383341 | 0.61 | MAPT (0.49) | MAPTMEN1KMT2AL3MBTL1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5942536-A | USEFUL FOR TREATING MIGRAINE | ELI LILLY AND COMPANY (US) | 1999-08-24 | — | — | US | disclosed |