Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 12/20 | 0.50 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8432850 | 0.91 | TP53 (0.55) | TP53MAPTABCB1HSP90AB1POLB | |
| SCHEMBL8431150 | 0.89 | TP53 (0.63) | TP53MAPTMEN1LMNAKMT2A | |
| SCHEMBL8433505 | 0.88 | POLB (0.63) | MAPTKMT2AABCB1POLBL3MBTL1 | |
| SCHEMBL7711545 | 0.84 | MAPT (0.71) | TP53MAPTMEN1LMNAKMT2A | |
| SCHEMBL8430992 | 0.82 | ABCB1 (0.62) | ABCB1L3MBTL1 | |
| SCHEMBL8430999 | 0.81 | ABCB1 (0.61) | MAPTABCB1 | |
| SCHEMBL8432829 | 0.80 | TP53 (0.65) | TP53MAPTMEN1KMT2AABCB1 | |
| SCHEMBL8432645 | 0.79 | MAPT (0.65) | MAPTMEN1LMNAKMT2AABCB1 | |
| SCHEMBL9005304 | 0.78 | ABCB1 (0.53) | MAPTABCB1HSP90AB1 | |
| SCHEMBL8435309 | 0.78 | ABCB1 (0.53) | MAPTABCB1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5981530-A | FOR TREATMENT OF ALLERGIC DISEASES | SENJU PHARMACEUTICAL CO., LTD. (JP) | 1999-11-09 | — | — | US | disclosed |
| EP-0735030-A1 | Piperazine derivative having antiallergic activity | Senju Pharmaceutical Co., Ltd. (JP) | 1996-10-02 | — | — | EP | disclosed |