SCHEMBL8435309

SCHEMBL8435309

CC(C)(C)c1cc(OCC(O)CN2CCN(c3ccccc3C(=O)O)CC2)ccc1O

nearest known ligand 0.53

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 13/20 0.53
HTR7 P34969 1/20 0.52
HSP90AB1 P08238 5/20 0.51
MAPT P10636 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9005304 1.00 ABCB1 (0.53) ABCB1HTR7HSP90AB1MAPT
SCHEMBL8432850 0.87 TP53 (0.55) ABCB1HSP90AB1MAPT
SCHEMBL8432829 0.85 TP53 (0.65) ABCB1HSP90AB1MAPT
SCHEMBL7708516 0.85 MAPT (0.70) HSP90AB1MAPT
Hydrochloric Acid SCHEMBL7711145 0.84 MAPT (0.69) HSP90AB1MAPT
SCHEMBL8432590 0.83 ABCB1 (0.61) ABCB1HTR7MAPT
SCHEMBL8434695 0.83 L3MBTL1 (0.67) ABCB1HTR7
SCHEMBL8432330 0.80 ABCB1 (0.60) ABCB1HTR7MAPT
SCHEMBL8432581 0.80 MAPT (0.73) ABCB1HTR7MAPT
SCHEMBL9005296 0.80 HSP90AB1 (0.51) ABCB1HSP90AB1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5981530-A FOR TREATMENT OF ALLERGIC DISEASES SENJU PHARMACEUTICAL CO., LTD. (JP) 1999-11-09 US claimed
US-5981530-A FOR TREATMENT OF ALLERGIC DISEASES SENJU PHARMACEUTICAL CO., LTD. (JP) 1999-11-09 US disclosed
EP-0735030-A1 Piperazine derivative having antiallergic activity Senju Pharmaceutical Co., Ltd. (JP) 1996-10-02 EP disclosed