Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | ABCB1 | P08183 | 12/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | HTR7 | P34969 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8430992 | 0.92 | ABCB1 (0.62) | L3MBTL1ABCB1HTR7 | |
| SCHEMBL8430999 | 0.91 | ABCB1 (0.61) | ABCB1MAPTHTR7 | |
| SCHEMBL8434402 | 0.88 | TP53 (0.53) | POLBL3MBTL1ABCB1KMT2AMAPT | |
| SCHEMBL8434205 | 0.85 | LMNA (0.69) | ABCB1MAPTHTR7 | |
| SCHEMBL8432645 | 0.83 | MAPT (0.65) | POLBABCB1GAAKMT2AMAPT | |
| SCHEMBL8432590 | 0.80 | ABCB1 (0.61) | POLBL3MBTL1ABCB1KMT2AMAPT | |
| SCHEMBL8434695 | 0.79 | L3MBTL1 (0.67) | L3MBTL1ABCB1TSHRKMT2AHTR7 | |
| SCHEMBL8431138 | 0.79 | MAPT (0.69) | ABCB1TSHRHSD17B10KMT2AMAPT | |
| SCHEMBL12259197 | 0.78 | MAPT (0.76) | POLBL3MBTL1TSHRRAB9AHSD17B10 | |
| SCHEMBL8431150 | 0.78 | TP53 (0.63) | ABCB1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5981530-A | FOR TREATMENT OF ALLERGIC DISEASES | SENJU PHARMACEUTICAL CO., LTD. (JP) | 1999-11-09 | — | — | US | disclosed |
| EP-0735030-A1 | Piperazine derivative having antiallergic activity | Senju Pharmaceutical Co., Ltd. (JP) | 1996-10-02 | — | — | EP | disclosed |