Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8076012 | 0.81 | TAAR1 (0.51) | ACHEBCHE | |
| SCHEMBL8076314 | 0.81 | TAAR1 (0.51) | ACHEBCHE | |
| SCHEMBL8077876 | 0.81 | TAAR1 (0.51) | ACHEBCHE | |
| SCHEMBL8076534 | 0.81 | TAAR1 (0.51) | ACHEBCHE | |
| SCHEMBL9827505 | 0.80 | SMN1; SMN2 (0.42) | ALDH1A1HPGDMAPTLMNAKDM4E | |
| SCHEMBL8072482 | 0.79 | TAAR1 (0.53) | BCHEKMT2AALOX5PTGS2 | |
| SCHEMBL9814061 | 0.78 | ALOX5 (0.59) | SLC2A1ALOX5PTGS2PPARA | |
| SCHEMBL9814049 | 0.78 | ALOX5 (0.59) | SLC2A1ALOX5PTGS2PPARA | |
| SCHEMBL9814043 | 0.78 | ALOX5 (0.59) | SLC2A1ALOX5PTGS2PPARA | |
| SCHEMBL16465705 | 0.78 | ALOX5 (0.48) | ALDH1A1HPGDUSP2TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5859017-A | PREVENTING OR TREATING ALLERGIES; INHIBITING INTRACELLULAR GENERATION OF PHOSPHATIDIC ACID AND DIACYLGLYCEROL | CELL THERAPEUTICS, INC. (US) | 1999-01-12 | — | — | US | disclosed |