Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.36 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.36 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.36 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.36 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.36 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.36 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.36 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.36 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.36 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.36 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.36 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.36 |
| ▸ | PSMB3 | P49720 | 1/20 | 0.36 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17123731 | 0.92 | ALOX5 (0.44) | ALOX5TRPV1ACHEPOLBPSMB11 | |
| SCHEMBL16466587 | 0.79 | ALOX5 (0.71) | ALOX5HTR2APTGS2 | |
| SCHEMBL16465418 | 0.79 | ALOX5 (0.71) | ALOX5HTR2APTGS2 | |
| SCHEMBL8434499 | 0.78 | ALDH1A1 (0.44) | ALOX5TRPV1ACHEALDH1A1USP2 | |
| SCHEMBL9578848 | 0.72 | ALOX5 (0.47) | ALOX5ACHEHTR2AHTR2CHTR2B | |
| SCHEMBL9578596 | 0.72 | ALOX5 (0.47) | ALOX5ACHEHTR2AHTR2CHTR2B | |
| SCHEMBL9578826 | 0.72 | ALOX5 (0.47) | ALOX5ACHEHTR2AHTR2CHTR2B | |
| SCHEMBL9578652 | 0.72 | ALOX5 (0.47) | ALOX5ACHEHTR2AHTR2CHTR2B | |
| SCHEMBL9578668 | 0.72 | ALOX5 (0.47) | ALOX5ACHEHTR2AHTR2CHTR2B | |
| SCHEMBL9578660 | 0.72 | ALOX5 (0.47) | ALOX5ACHEHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9957214-B2 | Multifunctional radical quenchers | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2018-05-01 | — | — | US | disclosed |
| US-9957214-B2 | Multifunctional radical quenchers | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2018-05-01 | — | — | US | disclosed |
| US-20150274628-A1 | MULTIFUNCTIONAL RADICAL QUENCHERS | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2015-10-01 | — | — | US | disclosed |
| US-20150274628-A1 | MULTIFUNCTIONAL RADICAL QUENCHERS | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2015-10-01 | — | — | US | disclosed |
| EP-2906207-A1 | MULTIFUNCTIONAL RADICAL QUENCHERS | Arizona Board of Regents on behalf of Arizona State University (US) | 2015-08-19 | — | — | EP | disclosed |
| WO-2014059158-A1 | MULTIFUNCTIONAL RADICAL QUENCHERS | ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA, ACTING FOR AN ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2014-04-17 | — | — | WO | disclosed |
| WO-2014059158-A1 | MULTIFUNCTIONAL RADICAL QUENCHERS | ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA, ACTING FOR AN ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2014-04-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150274628-A1 | MULTIFUNCTIONAL RADICAL QUENCHERS | SQOR, UQCRC1, PRDX5 | ALOX5 779/4885TRPV1 3171/4885ACHE 2574/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.