Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1230952 | 0.94 | ALDH1A1 (0.42) | HRH3ALDH1A1PKMHPGDGPR84 | |
| SCHEMBL28463361 | 0.92 | ALDH1A1 (0.44) | HRH3ALDH1A1PKMHPGDGPR84 | |
| Ammonia Solution, Strong SCHEMBL28347379 | 0.91 | ALDH1A1 (0.43) | HRH3ALDH1A1PKMHPGDGPR84 | |
| SCHEMBL5216842 | 0.79 | — | — | |
| SCHEMBL3840247 | 0.78 | HRH3 (0.42) | HRH3ALDH1A1MAPK1PARP1PKM | |
| SCHEMBL2037718 | 0.78 | HRH3 (0.42) | HRH3ALDH1A1MAPK1PARP1PKM | |
| Hydrochloric Acid SCHEMBL14743464 | 0.76 | HRH3 (0.41) | HRH3ALDH1A1MAPK1GSK3BPARP1 | |
| SCHEMBL3846855 | 0.76 | HRH3 (0.41) | HRH3ALDH1A1MAPK1GSK3BPARP1 | |
| SCHEMBL4988560 | 0.76 | HRH3 (0.41) | HRH3ALDH1A1MAPK1GSK3BPARP1 | |
| SCHEMBL5446824 | 0.76 | HRH3 (0.41) | HRH3ALDH1A1MAPK1GSK3BPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021237038-A1 | COMPETITIVE AND NONCOMPETITIVE INHIBITORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M5 | VANDERBILT UNIVERSITY (US) | 2021-11-25 | — | — | WO | disclosed |
| EP-3438106-A1 | ANTI-VIRAL COMPOUNDS | AbbVie Ireland Unlimited Company (IE) | 2019-02-06 | — | — | EP | disclosed |
| CN-1238262-C | Process for separating and recovering minim organic solvent from waste water using ion liquid | INST PROCESS ENG CAS (CN) | 2006-01-25 | — | — | CN | disclosed |
| CN-1594116-A | Process for separating and recovering minim organic solvent from waste water using ion liquid | INST PROCESS ENG CAS (CN) | 2005-03-16 | — | — | CN | disclosed |
| US-5929249-A | ANGIOTENSIN II RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-07-27 | — | — | US | disclosed |
| US-5728842-A | ANGIOTENSIN II RECEPTOR ANTAGONIST | SMITHKLINE BEECHAM CORPORATION (US) | 1998-03-17 | — | — | US | disclosed |
| EP-0653937-A4 | CHEMICAL COMPOUNDS. | SMITHKLINE BEECHAM CORP (US) | 1996-07-31 | — | — | EP | disclosed |
| EP-0653937-A1 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-05-24 | — | — | EP | disclosed |
| WO-1994000120-A1 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-01-06 | — | — | WO | disclosed |