Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8432677 | 0.86 | KMT2A (0.32) | KMT2AMAPT | |
| SCHEMBL8436775 | 0.77 | PTPN1 (0.37) | KMT2AMEN1ALDH1A1MAPTNPC1 | |
| SCHEMBL8432245 | 0.76 | MEN1 (0.35) | KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8918728 | 0.76 | KDM4E (0.45) | KMT2AKDM4EMEN1XDHNPSR1 | |
| SCHEMBL27523951 | 0.75 | KMT2A (0.41) | KMT2AKDM4EMEN1XDHNPSR1 | |
| SCHEMBL8433359 | 0.74 | KMT2A (0.45) | KMT2AKDM4EMEN1XDHNPSR1 | |
| SCHEMBL8101901 | 0.74 | KMT2A (0.40) | KMT2AKDM4EMEN1XDHNPSR1 | |
| SCHEMBL8433917 | 0.74 | KMT2A (0.40) | KMT2AKDM4EMEN1XDHNPSR1 | |
| SCHEMBL27417001 | 0.74 | NPC1 (0.30) | MAPTNPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL8921979 | 0.73 | TSHR (0.53) | KMT2AKDM4EMEN1NPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1060478-C | Substituted pyrazole derivatives | SCHERING AG (DE) | 2001-01-10 | — | — | CN | disclosed |
| US-5869686-A | Substituted pyrazole derivatives, processes for their preparation and their use as herbicides | HOECHST SCHERING AGREVO GMBH (DE) | 1999-02-09 | — | — | US | disclosed |
| EP-0663913-B1 | NEW SUBSTITUTED PYRAZOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1998-07-29 | — | — | EP | disclosed |
| US-5756424-A | POTENTIATION | HOECHST SCHERING AGREVO GMBH (DE) | 1998-05-26 | — | — | US | disclosed |
| CN-1161965-A | Substituted pyrazole derivatives | SCHERING AG (DE) | 1997-10-15 | — | — | CN | disclosed |
| US-5580986-A | HERBICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1996-12-03 | — | — | US | disclosed |
| CN-1087342-A | Novel substituted pyrazole derivatives, process for their preparation and their use as herbicides | SCHERING AG (DE) | 1994-06-01 | — | — | CN | disclosed |