Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 5/20 | 0.37 |
| ▸ | NPC1 | O15118 | 5/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8436203 | 0.87 | SPR (0.40) | NPC1RAB9AMAPTSMN1; SMN2KMT2A | |
| SCHEMBL8921979 | 0.85 | TSHR (0.53) | NPC1RAB9AMAPTALDH1A1TSHR | |
| SCHEMBL8436843 | 0.81 | MKNK1 (0.36) | NPC1RAB9ASMN1; SMN2RIPK2KMT2A | |
| SCHEMBL27417001 | 0.80 | NPC1 (0.30) | NPC1RAB9AMAPTHPGDTP53 | |
| SCHEMBL8436635 | 0.79 | MAPK1 (0.34) | NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL8434442 | 0.78 | RAB9A (0.50) | NPC1RAB9AMAPTALDH1A1TSHR | |
| SCHEMBL8432245 | 0.78 | MEN1 (0.35) | ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8434725 | 0.77 | KMT2A (0.42) | NPC1RAB9AMAPTALDH1A1HPGD | |
| SCHEMBL8434097 | 0.76 | TSHR (0.41) | NPC1RAB9AMAPTALDH1A1TSHR | |
| SCHEMBL8433921 | 0.72 | POLB (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869686-A | Substituted pyrazole derivatives, processes for their preparation and their use as herbicides | HOECHST SCHERING AGREVO GMBH (DE) | 1999-02-09 | — | — | US | disclosed |
| US-5756424-A | POTENTIATION | HOECHST SCHERING AGREVO GMBH (DE) | 1998-05-26 | — | — | US | disclosed |
| US-5580986-A | HERBICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1996-12-03 | — | — | US | disclosed |