Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27523951 | 0.87 | KMT2A (0.41) | KMT2AKDM4EMEN1ALDH1A1NPSR1 | |
| SCHEMBL8101901 | 0.86 | KMT2A (0.40) | KMT2AKDM4EMEN1ALDH1A1NPSR1 | |
| SCHEMBL8320789 | 0.79 | — | — | |
| SCHEMBL8607456 | 0.78 | — | — | |
| SCHEMBL8436837 | 0.77 | MEN1 (0.32) | KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL8110416 | 0.77 | RXRA (0.31) | — | |
| SCHEMBL8434725 | 0.74 | KMT2A (0.42) | KMT2AKDM4EMEN1ALDH1A1NPSR1 | |
| SCHEMBL8434475 | 0.73 | RXRA (0.31) | KMT2AMAPT | |
| SCHEMBL8919277 | 0.72 | KMT2A (0.43) | KMT2AKDM4EMEN1ALDH1A1NPSR1 | |
| SCHEMBL6976485 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869686-A | Substituted pyrazole derivatives, processes for their preparation and their use as herbicides | HOECHST SCHERING AGREVO GMBH (DE) | 1999-02-09 | — | — | US | disclosed |
| US-5756424-A | POTENTIATION | HOECHST SCHERING AGREVO GMBH (DE) | 1998-05-26 | — | — | US | disclosed |
| US-5580986-A | HERBICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1996-12-03 | — | — | US | disclosed |
| CN-1087342-A | Novel substituted pyrazole derivatives, process for their preparation and their use as herbicides | SCHERING AG (DE) | 1994-06-01 | — | — | CN | disclosed |