Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8576628 | 1.00 | PDK1 (0.38) | PDK1PDK2PDK3PDK4DPP8 | |
| SCHEMBL8437832 | 0.91 | DPP8 (0.38) | DPP8DPP9ALDH1A1MAPTLMNA | |
| SCHEMBL8435953 | 0.90 | PDK1 (0.45) | PDK1PDK2PDK3PDK4DPP8 | |
| SCHEMBL8435956 | 0.90 | PDK1 (0.45) | PDK1PDK2PDK3PDK4DPP8 | |
| SCHEMBL8588093 | 0.90 | PDK1 (0.45) | PDK1PDK2PDK3PDK4DPP8 | |
| SCHEMBL8434929 | 0.88 | DPP8 (0.42) | DPP8DPP9ALDH1A1MAPTLMNA | |
| SCHEMBL8543375 | 0.86 | PDK1 (0.42) | PDK1PDK2PDK3PDK4DPP8 | |
| SCHEMBL8441805 | 0.86 | PDK1 (0.42) | PDK1PDK2PDK3PDK4DPP8 | |
| SCHEMBL8537713 | 0.86 | PDK1 (0.42) | PDK1PDK2PDK3PDK4DPP8 | |
| SCHEMBL8435272 | 0.86 | PDK1 (0.42) | PDK1PDK2PDK3PDK4DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866564-A | STABILITY | SANKYO COMPANY, LIMITED (JP) | 1999-02-02 | — | — | US | disclosed |
| US-5712267-A | Carbapenem derivatives, their preparation and their use as antibiotics | SANKYO COMPANY,. LIMITED (JP) | 1998-01-27 | — | — | US | disclosed |
| EP-0560613-A1 | Antimicrobial carbapenem derivatives, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1993-09-15 | — | — | EP | disclosed |