Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 1/20 | 0.63 |
| ▸ | AGTR1 | P30556 | 7/20 | 0.46 |
| ▸ | AGTR2 | P50052 | 7/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3837125 | 0.94 | EDNRA (0.70) | EDNRAAGTR1AGTR2 | |
| SCHEMBL8521585 | 0.90 | EDNRA (0.61) | EDNRAAGTR1AGTR2 | |
| SCHEMBL8435201 | 0.90 | EDNRA (0.63) | EDNRAAGTR1AGTR2 | |
| SCHEMBL8435635 | 0.87 | EDNRA (0.58) | EDNRAAGTR1AGTR2 | |
| SCHEMBL7494119 | 0.87 | EDNRA (0.60) | EDNRAAGTR1AGTR2 | |
| SCHEMBL8434697 | 0.87 | EDNRA (0.58) | EDNRAAGTR1AGTR2 | |
| SCHEMBL8435630 | 0.87 | EDNRA (0.58) | EDNRAAGTR1AGTR2 | |
| SCHEMBL7497895 | 0.86 | EDNRA (0.73) | EDNRAAGTR1AGTR2 | |
| SCHEMBL7501847 | 0.86 | EDNRA (0.58) | EDNRAAGTR1AGTR2 | |
| SCHEMBL8043446 | 0.86 | EDNRA (0.59) | EDNRAAGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5932741-A | TREATING ILLNESSES RESULTING FROM ABNORMAL STIMULATION OF ENDOTHELIN RECEPTORS | HOECHST MARION ROUSSEL (FR) | 1999-08-03 | — | — | US | disclosed |
| US-5811444-A | IMIDAZOLE DERIVATIVES | ROUSSEL UCLAF (FR) | 1998-09-22 | — | — | US | disclosed |