Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8794230 | 0.88 | AGTR1 (0.66) | AGTR1AGTR2 | |
| SCHEMBL8434713 | 0.87 | AGTR1 (0.52) | AGTR1AGTR2 | |
| SCHEMBL8433980 | 0.83 | AGTR1 (0.63) | AGTR1AGTR2 | |
| SCHEMBL8436450 | 0.83 | AGTR1 (0.61) | AGTR1AGTR2 | |
| SCHEMBL9275255 | 0.82 | AGTR1 (0.64) | AGTR1AGTR2 | |
| SCHEMBL159 | 0.81 | AGTR1 (0.81) | AGTR1AGTR2 | |
| SCHEMBL8792091 | 0.80 | AGTR2 (0.59) | AGTR1AGTR2 | |
| SCHEMBL267 | 0.80 | AGTR1 (0.76) | AGTR1AGTR2 | |
| SCHEMBL640 | 0.80 | AGTR1 (0.77) | AGTR1AGTR2 | |
| SCHEMBL251 | 0.80 | AGTR1 (1.00) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0653937-A4 | CHEMICAL COMPOUNDS. | SMITHKLINE BEECHAM CORP (US) | 1996-07-31 | — | — | EP | claimed |
| EP-0653937-A1 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-05-24 | — | — | EP | claimed |
| WO-1994000120-A1 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-01-06 | — | — | WO | claimed |
| US-5929249-A | ANGIOTENSIN II RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-07-27 | — | — | US | disclosed |
| US-5728842-A | ANGIOTENSIN II RECEPTOR ANTAGONIST | SMITHKLINE BEECHAM CORPORATION (US) | 1998-03-17 | — | — | US | disclosed |
| EP-0653937-A4 | CHEMICAL COMPOUNDS. | SMITHKLINE BEECHAM CORP (US) | 1996-07-31 | — | — | EP | disclosed |
| EP-0653937-A1 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-05-24 | — | — | EP | disclosed |
| WO-1994000120-A1 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-01-06 | — | — | WO | disclosed |