Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24252518 | 0.84 | MAPT (0.38) | HTTMAPTSMN1; SMN2POLBHCAR2 | |
| SCHEMBL5144552 | 0.81 | HTT (0.39) | HTTMAPTSMN1; SMN2POLBHCAR2 | |
| SCHEMBL16213437 | 0.78 | TACR1 (0.36) | HTTMAPTSMN1; SMN2POLBHCAR2 | |
| SCHEMBL8438590 | 0.77 | CHRNB2 (0.38) | HCAR2CHRNB2CHRNA4 | |
| SCHEMBL26614750 | 0.76 | POLB (0.35) | HTTMAPTSMN1; SMN2POLBHCAR2 | |
| SCHEMBL670394 | 0.73 | — | — | |
| SCHEMBL30895742 | 0.73 | — | — | |
| SCHEMBL14157337 | 0.73 | — | — | |
| SCHEMBL7394006 | 0.72 | TACR1 (0.39) | HTTMAPTSMN1; SMN2KDM4ETACR1 | |
| SCHEMBL15163928 | 0.71 | HMGCR (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968947-A | INSECTICIDES, ACARICIDES, NEMATOCIDES | ZENECA LIMITED (GB) | 1999-10-19 | — | — | US | disclosed |