Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.31 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8520996 | 1.00 | MCHR1 (0.37) | MCHR1L3MBTL3HRH4HRH3PDK2 | |
| SCHEMBL7446784 | 0.90 | L3MBTL3 (0.41) | MCHR1L3MBTL3HRH4HRH3PDK2 | |
| SCHEMBL28820105 | 0.78 | PIM1 (0.32) | L3MBTL3 | |
| SCHEMBL28289828 | 0.78 | PIM1 (0.32) | L3MBTL3 | |
| SCHEMBL5422443 | 0.77 | DPP4 (0.38) | L3MBTL1 | |
| SCHEMBL28214294 | 0.77 | DPP4 (0.34) | — | |
| SCHEMBL21639868 | 0.77 | — | — | |
| SCHEMBL25341666 | 0.75 | — | — | |
| SCHEMBL4044055 | 0.75 | NPC1 (0.30) | — | |
| SCHEMBL5772842 | 0.75 | NPC1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866564-A | STABILITY | SANKYO COMPANY, LIMITED (JP) | 1999-02-02 | — | — | US | disclosed |
| US-5712267-A | Carbapenem derivatives, their preparation and their use as antibiotics | SANKYO COMPANY,. LIMITED (JP) | 1998-01-27 | — | — | US | disclosed |