Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.31 |
| ▸ | ENO1 | P06733 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28289828 | 1.00 | PIM1 (0.32) | PIM1L3MBTL3ENO1 | |
| SCHEMBL27953718 | 0.83 | — | — | |
| SCHEMBL28787824 | 0.81 | LMNA (0.33) | ENO1 | |
| SCHEMBL28253864 | 0.81 | DDB1 (0.34) | — | |
| SCHEMBL28965080 | 0.79 | MCHR1 (0.33) | — | |
| SCHEMBL18166955 | 0.79 | CHRM2 (0.33) | ENO1 | |
| SCHEMBL28291375 | 0.79 | OPRK1 (0.34) | L3MBTL3ENO1 | |
| SCHEMBL27698740 | 0.79 | ALDH1A1 (0.40) | ENO1 | |
| SCHEMBL8520996 | 0.78 | MCHR1 (0.37) | L3MBTL3 | |
| SCHEMBL8435141 | 0.78 | MCHR1 (0.37) | L3MBTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104822658-A | Fused Tricyclic Amides as Multiple Kinase Inhibitors | BEIGENE LTD | 2015-08-05 | — | — | CN | disclosed |