Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | METAP1 | P53582 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.42 |
| ▸ | NQO2 | P16083 | 3/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.42 |
| ▸ | CYP24A1 | Q07973 | 3/20 | 0.42 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7290713 | 0.90 | CYP24A1 (0.53) | ALDH1A1KDM4EMEN1GAAMAPT | |
| SCHEMBL972021 | 0.90 | CYP24A1 (0.53) | ALDH1A1KDM4EMEN1GAAMAPT | |
| SCHEMBL31650300 | 0.88 | CYP19A1 (0.48) | ALDH1A1KDM4EMEN1GAAMAPT | |
| SCHEMBL6383092 | 0.87 | ALDH1A1 (0.70) | ALDH1A1KDM4EMEN1GAAMAPT | |
| SCHEMBL345475 | 0.87 | ACHE (0.51) | CYP19A1ACHEMETAP1MTNR1ANQO2 | |
| SCHEMBL23459934 | 0.84 | ALDH1A1 (0.57) | ALDH1A1KDM4EMEN1GAAMAPT | |
| SCHEMBL23460007 | 0.84 | MEN1 (0.57) | ALDH1A1KDM4EMEN1GAAMAPT | |
| SCHEMBL449624 | 0.84 | MEN1 (0.57) | ALDH1A1KDM4EMEN1GAAMAPT | |
| SCHEMBL1877585 | 0.83 | ACHE (0.52) | ALDH1A1KDM4EMAPTCYP19A1ACHE | |
| SCHEMBL7979383 | 0.83 | CYP19A1 (0.55) | ALDH1A1KDM4EMAPTCYP19A1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102070431-B | Method for synthesizing saprorthoquinone | UNIV CHINA PHARMA | 2013-10-30 | — | — | CN | disclosed |
| CN-102070431-A | Method for synthesizing saprorthoquinone | UNIV CHINA PHARMA | 2011-05-25 | — | — | CN | disclosed |
| US-5945561-A | ANTIINFLAMMATORY AGENT, RHEUMATIC DISORDERS, SKIN DISORDERS,ANTISCARRING AGENT | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-08-31 | — | — | US | disclosed |
| WO-1998049136-A1 | RETINOID-LIKE COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-11-05 | — | — | WO | disclosed |
| EP-0641792-A1 | 1,2-Dithiole derivatives and therapeutic agents containing them | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1995-03-08 | — | — | EP | disclosed |
| US-5130339-A | Intestine and uterine motility modulators for reduction of intraocular pressure for glaucoma treatment | SANOFI (FR) | 1992-07-14 | — | — | US | disclosed |