Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 5/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 10/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9005291 | 0.89 | ABCB1 (0.48) | HSP90AB1ABCB1TP53MAPT | |
| SCHEMBL9005294 | 0.86 | SLC6A9 (0.43) | HSP90AB1ABCB1TP53MAPT | |
| SCHEMBL8432829 | 0.85 | TP53 (0.65) | HSP90AB1ABCB1TP53MAPT | |
| SCHEMBL8435309 | 0.80 | ABCB1 (0.53) | HSP90AB1ABCB1MAPT | |
| SCHEMBL9005304 | 0.80 | ABCB1 (0.53) | HSP90AB1ABCB1MAPT | |
| SCHEMBL9005292 | 0.77 | MEN1 (0.41) | HSP90AB1ABCB1MAPTALDH1A1 | |
| SCHEMBL8432850 | 0.76 | TP53 (0.55) | HSP90AB1ABCB1TP53MAPT | |
| SCHEMBL8431150 | 0.76 | TP53 (0.63) | HSP90AB1ABCB1TP53MAPT | |
| SCHEMBL9005293 | 0.73 | ABCB1 (0.49) | ABCB1TP53MAPTKDM4EALDH1A1 | |
| SCHEMBL8430938 | 0.73 | MEN1 (0.50) | HSP90AB1ABCB1TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735030-A1 | Piperazine derivative having antiallergic activity | Senju Pharmaceutical Co., Ltd. (JP) | 1996-10-02 | — | — | EP | claimed |
| EP-0735030-A1 | Piperazine derivative having antiallergic activity | Senju Pharmaceutical Co., Ltd. (JP) | 1996-10-02 | — | — | EP | disclosed |