Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 6/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6340896 | 0.77 | TACR1 (0.48) | TACR1GRIN1GRIN2BSIGMAR1ALDH1A1 | |
| SCHEMBL8804899 | 0.76 | TACR1 (0.47) | TACR1GRIN1GRIN2BSIGMAR1ALDH1A1 | |
| SCHEMBL8435472 | 0.76 | TACR1 (0.53) | TACR1GRIN1GRIN2BSIGMAR1LMNA | |
| SCHEMBL7227226 | 0.74 | TACR1 (0.58) | TACR1GRIN1GRIN2BSIGMAR1ALDH1A1 | |
| Alcohol SCHEMBL27874245 | 0.74 | TACR1 (0.53) | TACR1GRIN1GRIN2BSIGMAR1ALDH1A1 | |
| SCHEMBL6042725 | 0.71 | TACR1 (0.49) | TACR1GRIN1GRIN2BSIGMAR1 | |
| SCHEMBL20722666 | 0.71 | SIGMAR1 (0.47) | TACR1SIGMAR1ALDH1A1LMNA | |
| SCHEMBL16836134 | 0.70 | SIGMAR1 (0.64) | TACR1GRIN1GRIN2BSIGMAR1ALDH1A1 | |
| SCHEMBL6943959 | 0.70 | TACR1 (0.62) | TACR1GRIN1GRIN2BSIGMAR1ALDH1A1 | |
| SCHEMBL467266 | 0.70 | TACR1 (0.62) | TACR1GRIN1GRIN2BSIGMAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5998433-A | THERAPY FOR HYPERLIPIDEMIA; ATHEROSCLEROSIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-12-07 | — | — | US | disclosed |