SCHEMBL8435530

SCHEMBL8435530

CC(=O)Oc1cccc(OC(=O)c2ccccc2)c1

nearest known ligand 0.68

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.68
TDP1 Q9NUW8 3/20 0.68
KMT2A Q03164 8/20 0.59
MEN1 O00255 2/20 0.59
LMNA P02545 2/20 0.58
ELANE P08246 1/20 0.58
CYP3A4 P08684 1/20 0.58
MAPK1 P28482 1/20 0.55
ACHE P22303 1/20 0.53
ALDH1A1 P00352 2/20 0.52
L3MBTL1 Q9Y468 1/20 0.51
PKM P14618 1/20 0.51
GAA P10253 1/20 0.51
ESR1 P03372 1/20 0.51
ESR2 Q92731 1/20 0.51
PARP10 Q53GL7 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1785471 0.91 KMT2A (0.69) MAPTTDP1KMT2AMEN1LMNA
SCHEMBL14524425 0.90 HSD17B10 (0.57) MAPTTDP1KMT2AMEN1LMNA
Acetic Acid Phenyl Ester SCHEMBL5189342 0.89 MAPT (0.67) MAPTTDP1KMT2AMEN1LMNA
SCHEMBL16705193 0.87 ELANE (0.75) MAPTTDP1KMT2AMEN1LMNA
SCHEMBL8897429 0.86 MAPT (0.56) MAPTTDP1KMT2AMEN1LMNA
SCHEMBL10959120 0.86 MAPT (0.63) MAPTTDP1KMT2AMEN1LMNA
SCHEMBL411502 0.86 ESR1 (0.69) MAPTTDP1KMT2AMEN1LMNA
SCHEMBL2567322 0.86 MAOB (0.59) MAPTTDP1KMT2AMEN1ALDH1A1
SCHEMBL16429669 0.85 ELANE (0.79) MAPTTDP1KMT2AMEN1LMNA
SCHEMBL16429666 0.85 ELANE (0.72) MAPTTDP1KMT2AMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7709576-B2 Process for the preparation of sulfonate and sulfonate salt capped polyarylate resins with improved flow SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-05-04 US disclosed
US-20090247707-A1 PROCESS FOR THE PREPARATION OF SULFONATE AND SULFONATE SALT CAPPED POLYARYLATE RESINS WITH IMPROVED FLOW SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-10-01 US disclosed
EP-0699543-B1 Printing paper SONY CORP (JP) 1999-12-01 EP disclosed
US-5635441-A SHEET SUBSTRATE HAVING DYE RECEIVING LAYER OF CROSSLINKED COATING OBTAINED BY CURING MIXTURE OF BUTYRAL RESIN, VINYLPHENOLIC RESIN, POLYISOCYANATE; STORAGE STABLE IMAGES SONY CORPORATION (JP) 1997-06-03 US disclosed
EP-0699543-A1 Printing paper SONY CORPORATION (JP) 1996-03-06 EP disclosed