SCHEMBL411502

SCHEMBL411502

COc1cccc(OC(=O)c2ccccc2)c1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.69
ESR2 Q92731 1/20 0.69
PRSS1 P07477 1/20 0.64
ACR P10323 1/20 0.64
KMT2A Q03164 8/20 0.63
CES2 O00748 1/20 0.59
CES1 P23141 1/20 0.59
MEN1 O00255 5/20 0.59
MAPT P10636 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
CASP3 P42574 1/20 0.58
SENP8 Q96LD8 1/20 0.58
SENP7 Q9BQF6 1/20 0.58
SENP6 Q9GZR1 1/20 0.58
NPC1 O15118 3/20 0.58
RAB9A P51151 3/20 0.58
PARP1 P09874 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.55
NLRP3 Q96P20 1/20 0.55
LMNA P02545 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27595092 0.93 PRSS1 (0.72) ESR1ESR2PRSS1ACRKMT2A
SCHEMBL1785471 0.91 KMT2A (0.69) ESR1ESR2KMT2AMEN1MAPT
SCHEMBL28519972 0.89 ESR1 (0.73) ESR1ESR2KMT2ACES2CES1
SCHEMBL27744379 0.89 ESR1 (0.73) ESR1ESR2KMT2ACES2CES1
SCHEMBL13612569 0.88 KMT2A (0.77) ESR1ESR2KMT2ACES2CES1
SCHEMBL13890069 0.86 KMT2A (0.60) ESR1ESR2PRSS1ACRKMT2A
SCHEMBL14579669 0.86 PRSS1 (0.65) ESR1ESR2PRSS1ACRKMT2A
SCHEMBL18393365 0.86 ESR2 (0.69) ESR1ESR2PRSS1ACRKMT2A
SCHEMBL17275083 0.86 PRSS1 (0.65) ESR1ESR2PRSS1ACRKMT2A
SCHEMBL8435530 0.86 MAPT (0.68) ESR1ESR2KMT2AMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 176 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8545816-B2 1-(4-methoxyphenyl)-vinyl 4-tert-butylbenzoate; cosmetic, pharmaceutical, personal care and industrial preparations as sunscreens; ultraviolet radiation protection FERRER INTERNACIONAL, S.A. (ES) 2013-10-01 US claimed
US-20080206158-A1 Benzoic Acid Ester Compounds, Compositions, Uses and Methods Related Thereto FERRER INTERNACIONAL, S.A. (ES) 2008-08-28 US claimed
EP-1707558-A1 Benzoic acid ester compounds, compositions, uses and methods related thereto FERRER INTERNACIONAL, S.A. (ES) 2006-10-04 EP claimed
US-20240228773-A1 Articles and Structures with Colorable Electro-Static Dissipative (ESD) Polycarbonate Blends SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2024-07-11 US disclosed
EP-3092271-B1 COMPATIBILIZED COMPOSITIONS, ARTICLES FORMED THEREFROM, AND METHODS OF MANUFACTURE THEREOF SHPP GLOBAL TECH BV (NL) 2022-03-16 EP disclosed
US-10590240-B2 Thermoplastic composition with balanced chemical resistance and impact properties SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2020-03-17 US disclosed
US-20200070204-A1 POLYCARBONATE ARTICLES FOR CONSUMER ELECTRONICS SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2020-03-05 US disclosed
CN-105131298-B Silicyl polymerize benzoic acid ester compounds, purposes and combinations thereof 因特基马有限公司 2019-11-08 CN disclosed
US-10328017-B2 Silyl polymeric benzoic acid ester compounds, uses, and compositions thereof INTERQUIM, S.A. (ES) 2019-06-25 US disclosed
US-10196517-B2 Interior train components having low smoke and low heat release, and methods of their manufacture SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2019-02-05 US disclosed
US-20180215872-A1 THERMOPLASTIC COMPOSITION WITH BALANCED CHEMICAL RESISTANCE AND IMPACT PROPERTIES SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2018-08-02 US disclosed
US-20070066740-A1 Annular or tubular shaped articles of novel polymer blends CITIBANK, N.A., AS COLLATERAL AGENT 2007-03-22 US disclosed
US-20070066738-A1 Flame retardant polysulfone blends SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2007-03-22 US disclosed
US-20070065615-A1 ANNULAR OR TUBULAR SHAPED ARTICLES OF NOVEL POLYMER BLENDS CITIBANK, N.A., AS COLLATERAL AGENT 2007-03-22 US disclosed
US-20070027271-A1 WEATHERABLE, THERMOSTABLE POLYMERS HAVING IMPROVED FLOW COMPOSITION GENERAL ELECTRIC COMPANY (US) 2007-02-01 US disclosed
US-7169859-B2 Weatherable, thermostable polymers having improved flow composition GENERAL ELECTRIC COMPANY (US) 2007-01-30 US disclosed
US-20070015081-A1 Polycarbonate compositions having infrared absorbance, method of manufacture, and articles prepared therefrom SABIC GLOBAL TECHNOLOGIES IP B.V. (NL) 2007-01-18 US disclosed
WO-2007008476-A2 POLYCARBONATE COMPOSITIONS HAVING INFRARED ABSORBANCE, METHOD OF MANUFACTURE, AND ARTICLES PREPARED THEREFROM GENERAL ELECTRIC COMPANY (US) 2007-01-18 WO disclosed
EP-1707558-A1 Benzoic acid ester compounds, compositions, uses and methods related thereto FERRER INTERNACIONAL, S.A. (ES) 2006-10-04 EP disclosed
WO-2006100225-A2 BENZOIC ACID ESTER COMPOUNDS, COMPOSITIONS, USES AND METHODS RELATED THERETO FERRER INTERNACIONAL, S. A. (ES) 2006-09-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10328017-B2 Silyl polymeric benzoic acid ester compounds, uses, and compositions thereof SI, SUCLG1, CEL ESR1 122/4885ESR2 853/4885PRSS1 1904/4885
US-20080206158-A1 Benzoic Acid Ester Compounds, Compositions, Uses and Methods Related Thereto VKORC1, CYP51A1, CYP19A1 ESR1 79/4885ESR2 262/4885PRSS1 1935/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.