SCHEMBL8435596

SCHEMBL8435596

CCCCCCCCc1ccc(-c2cnc(-c3ccc(OC(=O)CC(CCCCCC)C(F)(F)F)cc3)nc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 6/20 0.46
MAPT P10636 4/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
MEN1 O00255 2/20 0.46
ALDH1A1 P00352 2/20 0.46
KMT2A Q03164 2/20 0.46
RAB9A P51151 2/20 0.46
KDM4E B2RXH2 1/20 0.46
USP2 O75604 1/20 0.46
GAA P10253 1/20 0.46
HPGD P15428 1/20 0.46
HSD17B10 Q99714 1/20 0.46
RARA P10276 1/20 0.42
MTOR P42345 1/20 0.42
THRB P10828 2/20 0.42
THRA P10827 1/20 0.42
S1PR4 O95977 2/20 0.40
S1PR1 P21453 2/20 0.40
S1PR3 Q99500 2/20 0.40
S1PR5 Q9H228 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8433914 0.91 RARB (0.46) RARBMAPTSMN1; SMN2ALDH1A1RAB9A
SCHEMBL8432006 0.91 RARB (0.46) RARBMAPTSMN1; SMN2ALDH1A1RAB9A
SCHEMBL9624326 0.91 RARB (0.54) RARBMAPTSMN1; SMN2MEN1ALDH1A1
SCHEMBL8436583 0.89 RARB (0.46) RARBMAPTSMN1; SMN2ALDH1A1RAB9A
SCHEMBL8433923 0.88 RARB (0.45) RARBMAPTSMN1; SMN2ALDH1A1RAB9A
SCHEMBL8434200 0.88 RARB (0.45) RARBMAPTSMN1; SMN2ALDH1A1RAB9A
SCHEMBL10427117 0.87 RARB (0.48) RARBMAPTSMN1; SMN2MEN1ALDH1A1
SCHEMBL8432234 0.86 KMT2A (0.43) RARBMAPTSMN1; SMN2MEN1ALDH1A1
SCHEMBL6254987 0.85 RARB (0.47) RARBMAPTSMN1; SMN2MEN1ALDH1A1
SCHEMBL10427268 0.85 RARB (0.48) RARBMAPTSMN1; SMN2MEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0499221-B1 Optically active compound, liquid crystal composition, liquid crystal device, display apparatus and display method CANON KK (JP) 1999-12-08 EP disclosed
US-5281362-A Ferroelectric liquid crystals for optics CANON KABUSHIKI KAISHA (JP) 1994-01-25 US disclosed
EP-0499221-A1 Optically active compound, liquid crystal composition, liquid crystal device, display apparatus and display method CANON KABUSHIKI KAISHA (JP) 1992-08-19 EP disclosed