Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 3/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8435596 | 0.91 | RARB (0.46) | RARBMAPTSMN1; SMN2RAB9AHSD17B10 | |
| SCHEMBL8436583 | 0.88 | RARB (0.46) | RARBMAPTSMN1; SMN2RAB9AHSD17B10 | |
| SCHEMBL8434200 | 0.87 | RARB (0.45) | RARBMAPTSMN1; SMN2RAB9AHSD17B10 | |
| SCHEMBL8433923 | 0.87 | RARB (0.45) | RARBMAPTSMN1; SMN2RAB9AHSD17B10 | |
| SCHEMBL8432234 | 0.86 | KMT2A (0.43) | RARBMAPTSMN1; SMN2RAB9AMEN1 | |
| SCHEMBL8433914 | 0.86 | RARB (0.46) | RARBMAPTSMN1; SMN2RAB9AHSD17B10 | |
| SCHEMBL8432006 | 0.86 | RARB (0.46) | RARBMAPTSMN1; SMN2RAB9AHSD17B10 | |
| SCHEMBL10702141 | 0.84 | RARB (0.55) | RARBMAPTSMN1; SMN2RAB9AHSD17B10 | |
| SCHEMBL9362083 | 0.84 | RARB (0.55) | RARBMAPTSMN1; SMN2RAB9AHSD17B10 | |
| SCHEMBL9351975 | 0.84 | MAPT (0.56) | RARBMAPTSMN1; SMN2RAB9AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301511-B1 | OPTICALLY ACTIVE COMPOUND AND LIQUID CRYSTAL COMPOSITION CONTAINING SAME | CANON KABUSHIKI KAISHA (JP) | 1992-01-22 | — | — | EP | disclosed |
| US-5073306-A | Trifluoromethylalkyl substituted | CANON KABUSHIKI KAISHA (JP) | 1991-12-17 | — | — | US | disclosed |
| US-4918213-A | HAVING A TRIFLUOROMETHYL GROUP ATTACHED TO ASYMMETRIC CARBON ATOM; STABLE; OPTICAL DEVICES | CANON KABUSHIKI KAISHA (JP) | 1990-04-17 | — | — | US | disclosed |
| EP-0301511-A1 | Optically active compound and liquid crystal composition containing same | CANON KABUSHIKI KAISHA (JP) | 1989-02-01 | — | — | EP | disclosed |