Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 8/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.42 |
| ▸ | RELA | Q04206 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8434200 | 1.00 | RARB (0.45) | RARBNPC1SMN1; SMN2LMNANFKB1 | |
| SCHEMBL8432006 | 0.95 | RARB (0.46) | RARBNPC1SMN1; SMN2LMNANFKB1 | |
| SCHEMBL8433914 | 0.95 | RARB (0.46) | RARBNPC1SMN1; SMN2LMNANFKB1 | |
| SCHEMBL8436583 | 0.93 | RARB (0.46) | RARBNPC1SMN1; SMN2LMNANFKB1 | |
| SCHEMBL9625052 | 0.88 | RARB (0.51) | RARBNPC1SMN1; SMN2LMNANFKB1 | |
| SCHEMBL8435596 | 0.88 | RARB (0.46) | RARBSMN1; SMN2MAPTRAB9AKDM4E | |
| SCHEMBL8432234 | 0.88 | KMT2A (0.43) | RARBNPC1SMN1; SMN2LMNANFKB1 | |
| SCHEMBL9624326 | 0.87 | RARB (0.54) | RARBNPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL8436678 | 0.84 | RAB9A (0.50) | RARBNPC1SMN1; SMN2MAPTRAB9A | |
| SCHEMBL9357152 | 0.83 | RARB (0.48) | RARBNPC1SMN1; SMN2LMNANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5065276-A | — | — | None | — | — | JP | disclosed |
| EP-0499221-B1 | Optically active compound, liquid crystal composition, liquid crystal device, display apparatus and display method | CANON KK (JP) | 1999-12-08 | — | — | EP | disclosed |
| US-5281362-A | Ferroelectric liquid crystals for optics | CANON KABUSHIKI KAISHA (JP) | 1994-01-25 | — | — | US | disclosed |
| JP-H0565276-A | OPTICALLY ACTIVE COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL ELEMENT CONTAINING THE SAME AND DISPLAYING METHOD AND DEVICE USING THE SAME | CANON INC | 1993-03-19 | — | — | JP | disclosed |
| EP-0499221-A1 | Optically active compound, liquid crystal composition, liquid crystal device, display apparatus and display method | CANON KABUSHIKI KAISHA (JP) | 1992-08-19 | — | — | EP | disclosed |