Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 2/20 | 0.36 |
| ▸ | KCNJ1 | P48048 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoromethanesulfonic Acid SCHEMBL8544331 | 0.98 | KDM4E (0.35) | HRH2HRH1CCR5KCNJ1KCNH2 | |
| Trifluoromethanesulfonic Acid SCHEMBL8438040 | 0.93 | HRH2 (0.36) | HRH2HRH1CCR5KCNJ1KCNH2 | |
| SCHEMBL8437995 | 0.93 | HRH2 (0.41) | HRH2HRH1KCNJ1KCNH2KDM4E | |
| SCHEMBL8439573 | 0.93 | HRH2 (0.41) | HRH2HRH1KCNJ1KCNH2KDM4E | |
| SCHEMBL8434840 | 0.93 | HRH2 (0.41) | HRH2HRH1KCNJ1KCNH2KDM4E | |
| Trifluoromethanesulfonic Acid SCHEMBL8537325 | 0.92 | CCR5 (0.37) | HRH2HRH1CCR5KCNJ1KCNH2 | |
| Trifluoromethanesulfonic Acid SCHEMBL9125762 | 0.91 | DPP8 (0.36) | HRH2HRH1CCR5KCNJ1KCNH2 | |
| Trifluoromethanesulfonic Acid SCHEMBL8438408 | 0.89 | CCR5 (0.36) | HRH2HRH1CCR5KCNJ1KCNH2 | |
| Trifluoromethanesulfonic Acid SCHEMBL9125753 | 0.89 | CCR5 (0.39) | CCR5ALDH1A1DPP8DPP9PDK1 | |
| Trifluoromethanesulfonic Acid SCHEMBL8438327 | 0.88 | CCR5 (0.36) | CCR5KCNJ1DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866564-A | STABILITY | SANKYO COMPANY, LIMITED (JP) | 1999-02-02 | — | — | US | disclosed |
| US-5712267-A | Carbapenem derivatives, their preparation and their use as antibiotics | SANKYO COMPANY,. LIMITED (JP) | 1998-01-27 | — | — | US | disclosed |