Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 2/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoromethanesulfonic Acid SCHEMBL8435643 | 0.98 | HRH2 (0.37) | KDM4EALDH1A1TDP1HRH2HRH1 | |
| Trifluoromethanesulfonic Acid SCHEMBL9125762 | 0.94 | DPP8 (0.36) | KDM4EALDH1A1TDP1HRH2HRH1 | |
| Trifluoromethanesulfonic Acid SCHEMBL8438408 | 0.92 | CCR5 (0.36) | KDM4EALDH1A1TDP1HRH2HRH1 | |
| Trifluoromethanesulfonic Acid SCHEMBL8438040 | 0.91 | HRH2 (0.36) | KDM4EALDH1A1TDP1HRH2HRH1 | |
| SCHEMBL8439573 | 0.91 | HRH2 (0.41) | KDM4EALDH1A1TDP1HRH2HRH1 | |
| SCHEMBL8434840 | 0.91 | HRH2 (0.41) | KDM4EALDH1A1TDP1HRH2HRH1 | |
| SCHEMBL8437995 | 0.91 | HRH2 (0.41) | KDM4EALDH1A1TDP1HRH2HRH1 | |
| Trifluoromethanesulfonic Acid SCHEMBL8537325 | 0.90 | CCR5 (0.37) | KDM4EALDH1A1HRH2HRH1CCR5 | |
| Trifluoromethanesulfonic Acid SCHEMBL8435997 | 0.89 | DPP8 (0.36) | CCR5DPP8DPP9 | |
| Trifluoromethanesulfonic Acid SCHEMBL9127836 | 0.89 | CCR5 (0.37) | CCR5DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0518558-B1 | 1-Methylcarbapenem derivatives, their preparation and their use as antibiotics | SANKYO CO (JP) | 1998-09-02 | — | — | EP | disclosed |
| US-5712267-A | Carbapenem derivatives, their preparation and their use as antibiotics | SANKYO COMPANY,. LIMITED (JP) | 1998-01-27 | — | — | US | disclosed |
| US-5420119-A | Bactericides | SANKYO COMPANY, LIMITED (JP) | 1995-05-30 | — | — | US | disclosed |
| US-5310735-A | Carbapenem derivatives having antibiotic activity, their preparation and their use | SANKYO COMPANY, LIMITED (JP) | 1994-05-10 | — | — | US | disclosed |
| EP-0518558-A1 | 1-Methylcarbapenem derivatives, their preparation and their use as antibiotics | Sankyo Company Limited (JP) | 1992-12-16 | — | — | EP | disclosed |