SCHEMBL8435726

CC(C)=CCCC(C)=CC[C@@]1(n2ccc(=O)[nH]c2=O)O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]1O.CC(C)=CCCC(C)=CC[C@@]1(n2cnc3c(=O)[nH]c(=O)[nH]c32)O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]1O

nearest known ligand 0.41

Predicted protein targets (top 5)

	gene	UniProt	supporting neighbours	confidence
▸	P2RY2	P41231	14/20	0.41

▸	P2RY6	Q15077	10/20	0.41

▸	P2RY4	P51582	9/20	0.41

▸	POLA1	P09884	1/20	0.39

▸	P2RY14	Q15391	1/20	0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL8439668	0.94	P2RX3 (0.36)	P2RY2P2RY6
SCHEMBL8439436	0.94	FNTA (0.37)	—
SCHEMBL8439487	0.90	P2RY2 (0.49)	P2RY2P2RY6P2RY4POLA1
SCHEMBL8439812	0.89	P2RY2 (0.48)	P2RY2P2RY6P2RY4POLA1
SCHEMBL8436518	0.88	P2RX3 (0.40)	P2RY2P2RY6P2RY4
SCHEMBL8440653	0.83	P2RY2 (0.54)	P2RY2P2RY6P2RY4POLA1
SCHEMBL8441414	0.82	POLG (0.46)	P2RY2P2RY6P2RY4POLA1
SCHEMBL8439180	0.82	POLG (0.46)	P2RY2P2RY6P2RY4POLA1
SCHEMBL8435820	0.81	P2RX3 (0.40)	P2RY2P2RY6P2RY4
SCHEMBL8440907	0.81	P2RX3 (0.42)	P2RY2P2RY6P2RY4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-5902793-A	ADMINISTERING TO MAMMAL GAMMA-MONOALKYL- OR GAMMA-ALKENYL-NUCLEOSIDE OR DEOXYNUCLEOSIDE TRIPHOSPHATE	ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US)	1999-05-11	—	—	US	disclosed