Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 10/20 | 0.42 |
| ▸ | IKBKB | O14920 | 7/20 | 0.42 |
| ▸ | RARB | P10826 | 8/20 | 0.41 |
| ▸ | RARG | P13631 | 8/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.40 |
| ▸ | GOT1 | P17174 | 1/20 | 0.40 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8428653 | 0.93 | RARA (0.50) | RARAIKBKBRARBRARGMEN1 | |
| SCHEMBL8397880 | 0.90 | RARA (0.48) | RARAIKBKBRARBRARGMEN1 | |
| SCHEMBL8433862 | 0.85 | RARA (0.54) | RARAIKBKBRARBRARGMEN1 | |
| SCHEMBL8431711 | 0.85 | RARA (0.43) | RARAIKBKBRARBRARGMEN1 | |
| SCHEMBL8433871 | 0.85 | RARA (0.54) | RARAIKBKBRARBRARGMEN1 | |
| SCHEMBL8436677 | 0.84 | RARA (0.59) | RARAIKBKBRARBRARGMEN1 | |
| SCHEMBL8431940 | 0.84 | CYP3A4 (0.49) | RARAIKBKBRARBRARGMEN1 | |
| SCHEMBL8434724 | 0.84 | RARA (0.44) | RARAIKBKBRARBRARGMEN1 | |
| SCHEMBL8399150 | 0.83 | RARA (0.40) | RARAIKBKBRARBRARGMEN1 | |
| SCHEMBL8394318 | 0.83 | IKBKB (0.41) | RARAIKBKBRARBRARGMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0776881-B1 | Bi-aromatic compounds comprising an adamantyl group in para-position, pharmaceutical and cosmetic compositions containing them and their utilization | CIRD GALDERMA (FR) | 1999-12-08 | — | — | EP | claimed |