Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 8/20 | 0.61 |
| ▸ | ACHE | P22303 | 7/20 | 0.49 |
| ▸ | CASP2 | P42575 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10972245 | 0.93 | ACHE (0.55) | EPHX1ACHE | |
| SCHEMBL12599419 | 0.88 | EPHX1 (0.59) | EPHX1 | |
| SCHEMBL27050907 | 0.85 | EPHX1 (0.66) | EPHX1ACHE | |
| SCHEMBL10252302 | 0.85 | EPHX1 (0.66) | EPHX1ACHE | |
| SCHEMBL10304512 | 0.85 | EPHX1 (0.66) | EPHX1ACHE | |
| SCHEMBL19508891 | 0.85 | EPHX1 (0.66) | EPHX1ACHE | |
| SCHEMBL11419405 | 0.85 | CHRNB2 (0.46) | EPHX1ACHE | |
| SCHEMBL21203082 | 0.84 | EPHX1 (0.42) | EPHX1ACHE | |
| SCHEMBL16443675 | 0.84 | EPHX1 (0.63) | EPHX1ACHECASP2 | |
| SCHEMBL29161883 | 0.84 | EPHX1 (0.63) | EPHX1ACHECASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5990195-A | POLYMERIZING A FILLER, A (METH)ACRYLATE AND PROMOTER AT A PRESSURE OF 50-300 MPA AND TEMPERATURE OF 100-200 DEGREES C.; MILLING USING A CAD/CAM DEVICE; ESTHETICS; MECHANICAL PROPERTIES; FREE OF FOAM AND MONOMER; CROWNS; INLAYS; CROWNS | GC CORPORATION (JP) | 1999-11-23 | — | — | US | disclosed |