Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.39 |
| ▸ | NPBWR1 | P48145 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8439623 | 0.97 | DPP8 (0.43) | DPP8DPP9MCHR1NPBWR1ALDH1A1 | |
| SCHEMBL8437832 | 0.90 | DPP8 (0.38) | DPP8DPP9MCHR1NPBWR1ALDH1A1 | |
| SCHEMBL8434929 | 0.86 | DPP8 (0.42) | DPP8DPP9MCHR1NPBWR1ALDH1A1 | |
| SCHEMBL8540916 | 0.84 | GAA (0.42) | DPP8DPP9ALDH1A1MAPTLMNA | |
| SCHEMBL8439220 | 0.83 | DPP8 (0.43) | DPP8DPP9ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8436425 | 0.83 | MCHR1 (0.39) | MCHR1NPBWR1ALDH1A1MAPTATM | |
| Trifluoromethanesulfonic Acid SCHEMBL8435163 | 0.82 | DPP8 (0.38) | DPP8DPP9MCHR1NPBWR1ALDH1A1 | |
| SCHEMBL8435987 | 0.82 | HSD11B1 (0.44) | DPP8DPP9ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8435984 | 0.82 | HSD11B1 (0.44) | DPP8DPP9ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8439764 | 0.81 | EPHX2 (0.39) | DPP8DPP9MCHR1NPBWR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866564-A | STABILITY | SANKYO COMPANY, LIMITED (JP) | 1999-02-02 | — | — | US | disclosed |
| EP-0560613-B1 | Antimicrobial carbapenem derivatives, their preparation and their therapeutic use | SANKYO CO (JP) | 1998-11-25 | — | — | EP | disclosed |
| EP-0560613-A1 | Antimicrobial carbapenem derivatives, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1993-09-15 | — | — | EP | disclosed |