Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8440242 | 0.96 | ALDH1A1 (0.37) | EPHX2ALDH1A1MAPTSIGMAR1GAA | |
| SCHEMBL9574302 | 0.92 | ALDH1A1 (0.39) | ALDH1A1MAPTGAADPP8DPP9 | |
| SCHEMBL8447158 | 0.86 | TPSAB1 (0.39) | ALDH1A1MAPTGAADPP8DPP9 | |
| SCHEMBL8439874 | 0.86 | EPHX2 (0.35) | EPHX2ALDH1A1MAPTSIGMAR1GAA | |
| SCHEMBL8436695 | 0.85 | HSD11B1 (0.35) | EPHX2ALDH1A1MAPTSIGMAR1DPP8 | |
| SCHEMBL8440441 | 0.85 | HSD11B1 (0.35) | EPHX2ALDH1A1MAPTSIGMAR1DPP8 | |
| SCHEMBL8435984 | 0.84 | HSD11B1 (0.44) | EPHX2ALDH1A1MAPTSIGMAR1KMT2A | |
| SCHEMBL8435987 | 0.84 | HSD11B1 (0.44) | EPHX2ALDH1A1MAPTSIGMAR1KMT2A | |
| SCHEMBL8439767 | 0.84 | EPHX2 (0.39) | EPHX2ALDH1A1SIGMAR1KMT2ADRD4 | |
| SCHEMBL8435826 | 0.84 | EPHX2 (0.38) | EPHX2ALDH1A1MAPTSIGMAR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866564-A | STABILITY | SANKYO COMPANY, LIMITED (JP) | 1999-02-02 | — | — | US | disclosed |
| EP-0518558-B1 | 1-Methylcarbapenem derivatives, their preparation and their use as antibiotics | SANKYO CO (JP) | 1998-09-02 | — | — | EP | disclosed |
| US-5712267-A | Carbapenem derivatives, their preparation and their use as antibiotics | SANKYO COMPANY,. LIMITED (JP) | 1998-01-27 | — | — | US | disclosed |
| EP-0518558-A1 | 1-Methylcarbapenem derivatives, their preparation and their use as antibiotics | Sankyo Company Limited (JP) | 1992-12-16 | — | — | EP | disclosed |