Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP7 | P09237 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8521567 | 0.90 | TP53 (0.43) | MAPTSMN1; SMN2POLBKDM4E | |
| SCHEMBL8521564 | 0.90 | TP53 (0.43) | MAPTSMN1; SMN2POLBKDM4E | |
| Hydrochloric Acid SCHEMBL8579092 | 0.86 | HPGD (0.40) | MAPTSMN1; SMN2ALDH1A1HPGDKMT2A | |
| SCHEMBL7454797 | 0.84 | ALDH1A1 (0.42) | MAPTSMN1; SMN2POLBALDH1A1HPGD | |
| SCHEMBL8440250 | 0.84 | ALDH1A1 (0.42) | MAPTSMN1; SMN2POLBALDH1A1HPGD | |
| SCHEMBL8604028 | 0.83 | IDO1 (0.43) | MAPTSMN1; SMN2ALDH1A1HPGDMAOB | |
| SCHEMBL8439880 | 0.83 | IDO1 (0.43) | MAPTSMN1; SMN2ALDH1A1HPGDMAOB | |
| SCHEMBL8436470 | 0.80 | GAA (0.41) | MAPTSMN1; SMN2ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL9127639 | 0.79 | KCNJ1 (0.41) | MAPTSMN1; SMN2ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL8540916 | 0.78 | GAA (0.42) | MAPTSMN1; SMN2ALDH1A1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866564-A | STABILITY | SANKYO COMPANY, LIMITED (JP) | 1999-02-02 | — | — | US | disclosed |
| EP-0518558-B1 | 1-Methylcarbapenem derivatives, their preparation and their use as antibiotics | SANKYO CO (JP) | 1998-09-02 | — | — | EP | disclosed |
| US-5712267-A | Carbapenem derivatives, their preparation and their use as antibiotics | SANKYO COMPANY,. LIMITED (JP) | 1998-01-27 | — | — | US | disclosed |
| EP-0518558-A1 | 1-Methylcarbapenem derivatives, their preparation and their use as antibiotics | Sankyo Company Limited (JP) | 1992-12-16 | — | — | EP | disclosed |