Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8604028 | 1.00 | IDO1 (0.43) | IDO1HTRA1ALDH1A1HPGDSIRT2 | |
| SCHEMBL7454797 | 0.89 | ALDH1A1 (0.42) | IDO1HTRA1ALDH1A1HPGDEPHX1 | |
| SCHEMBL8440250 | 0.89 | ALDH1A1 (0.42) | IDO1HTRA1ALDH1A1HPGDEPHX1 | |
| Hydrochloric Acid SCHEMBL8579092 | 0.84 | HPGD (0.40) | IDO1HTRA1ALDH1A1HPGDEPHX1 | |
| SCHEMBL8435919 | 0.83 | MAPT (0.50) | HTRA1ALDH1A1HPGDSMN1; SMN2MAPT | |
| SCHEMBL9202402 | 0.82 | HTRA1 (0.44) | IDO1HTRA1ALDH1A1HPGDSIRT2 | |
| SCHEMBL8521564 | 0.80 | TP53 (0.43) | SMN1; SMN2MAPT | |
| SCHEMBL8521567 | 0.80 | TP53 (0.43) | SMN1; SMN2MAPT | |
| SCHEMBL7165527 | 0.78 | HTRA1 (0.45) | HTRA1ALDH1A1HPGDEPHX1DPP4 | |
| SCHEMBL7143325 | 0.75 | CA12 (0.41) | HTRA1ALDH1A1HPGDDPP4DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866564-A | STABILITY | SANKYO COMPANY, LIMITED (JP) | 1999-02-02 | — | — | US | disclosed |
| EP-0518558-B1 | 1-Methylcarbapenem derivatives, their preparation and their use as antibiotics | SANKYO CO (JP) | 1998-09-02 | — | — | EP | disclosed |
| US-5712267-A | Carbapenem derivatives, their preparation and their use as antibiotics | SANKYO COMPANY,. LIMITED (JP) | 1998-01-27 | — | — | US | disclosed |
| EP-0518558-A1 | 1-Methylcarbapenem derivatives, their preparation and their use as antibiotics | Sankyo Company Limited (JP) | 1992-12-16 | — | — | EP | disclosed |