SCHEMBL8435986

SCHEMBL8435986

Cc1cccc(NC(=O)c2ccc(O)cc2O)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.60
KMT2A Q03164 2/20 0.60
ALDH1A1 P00352 1/20 0.60
RXFP1 Q9HBX9 1/20 0.58
SORT1 Q99523 1/20 0.57
L3MBTL1 Q9Y468 1/20 0.56
SRC P12931 1/20 0.56
MMP1 P03956 2/20 0.55
MMP2 P08253 2/20 0.55
MMP9 P14780 2/20 0.55
PLG P00747 2/20 0.55
KLK1 P06870 2/20 0.55
KLK6 Q92876 2/20 0.55
ESRRG P62508 1/20 0.54
AKR1C3 P42330 1/20 0.54
HSD17B10 Q99714 1/20 0.54
KCNK3 O14649 2/20 0.54
KCNK9 Q9NPC2 2/20 0.54
KCNH2 Q12809 1/20 0.54
TERT O14746 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24332744 0.85 SRC (0.80) MEN1KMT2AALDH1A1RXFP1L3MBTL1
SCHEMBL16941525 0.84 MEN1 (0.72) MEN1KMT2AALDH1A1RXFP1L3MBTL1
SCHEMBL15682961 0.84 ALDH1A1 (0.57) MEN1KMT2AALDH1A1L3MBTL1SRC
SCHEMBL8438123 0.83 NPC1 (0.66) MEN1KMT2AALDH1A1PLGKLK1
SCHEMBL1096228 0.82 KMT2A (0.68) MEN1KMT2AALDH1A1L3MBTL1SRC
SCHEMBL9080921 0.82 MEN1 (0.66) MEN1KMT2AALDH1A1RXFP1KCNK3
SCHEMBL2272936 0.81 RAB9A (0.61) KMT2AALDH1A1RXFP1SRCMMP1
SCHEMBL2743105 0.81 KMT2A (0.74) MEN1KMT2AALDH1A1L3MBTL1SRC
SCHEMBL14363224 0.80 MEN1 (0.73) MEN1KMT2AALDH1A1RXFP1MMP1
SCHEMBL14514566 0.80 PLG (0.67) MEN1KMT2AALDH1A1PLGKLK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0756943-B1 Heat sensitive recording material NEW OJI PAPER CO LTD (JP) 1999-12-22 EP disclosed
US-5753588-A COMPRISING INDOLYLDIAZAPHTHALIDE BASIC DYE, DIPHENYL SULFONE OR BENZANILIDE DERIVATIVE COLOR ACCEPTOR NEW OJI PAPER COMPANY LIMITED (JP) 1998-05-19 US disclosed
EP-0756943-A1 Heat sensitive recording material NEW OJI PAPER CO., LTD. (JP) 1997-02-05 EP disclosed