SCHEMBL8436003

SCHEMBL8436003

C=Cc1ccc(CS(=O)(=O)CCOS(=O)(=O)c2ccc(C)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 5/20 0.43
▸ TDP1 Q9NUW8 1/20 0.40
▸ CYP2C19 P33261 2/20 0.39
▸ ALDH1A1 P00352 1/20 0.38
▸ CA1 P00915 3/20 0.37
▸ CA9 Q16790 3/20 0.37
▸ POLB P06746 2/20 0.37
▸ CA2 P00918 2/20 0.37
▸ CYP3A4 P08684 3/20 0.37
▸ RAB9A P51151 1/20 0.37
▸ CA12 O43570 2/20 0.35
▸ CYP2D6 P10635 1/20 0.35
▸ TSHR P16473 1/20 0.35
▸ MEN1 O00255 1/20 0.34
▸ TP53 P04637 1/20 0.34
▸ MAPT P10636 1/20 0.34
▸ CYP24A1 Q07973 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1617207 0.81 CA2 (0.50) KMT2ATDP1CYP2C19ALDH1A1CA1
SCHEMBL7589721 0.79 TDP1 (0.50) TDP1ALDH1A1CA1CA9RAB9A
SCHEMBL8970130 0.78 CYP24A1 (0.39) KMT2ACYP2C19ALDH1A1CA1CA9
SCHEMBL316861 0.78 SMN1; SMN2 (0.39) KMT2ATDP1ALDH1A1CA1CA9
SCHEMBL3445522 0.77 CA12 (0.53) TDP1ALDH1A1CA1CA9POLB
SCHEMBL15803394 0.76 MAPT (0.47) KMT2ATDP1CYP2C19ALDH1A1CA1
SCHEMBL15567462 0.74 KMT2A (0.54) KMT2ACYP2C19ALDH1A1CA1CA9
SCHEMBL4903485 0.74 TDP1 (0.47) KMT2ATDP1CYP2C19ALDH1A1CA1
SCHEMBL14275049 0.74 TDP1 (0.50) TDP1ALDH1A1CA1CA9POLB
SCHEMBL1556981 0.74 ALDH1A1 (0.46) KMT2ACYP2C19ALDH1A1CA1CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5374516-A Covalently attached to polymer particles of ethylenically unsaturated monomers with reactive alkylsulfonyl or halogen groups; detecting hormones, drugs, steroids in urine, blood, saliva EASTMAN KODAK COMPANY (US) 1994-12-20 — — US claimed
US-5177023-A Immunology EASTMAN KODAK COMPANY (US) 1993-01-05 — — US claimed
US-5888723-A SENSITIVE HYBRIDIZATION ASSAY USING NUCLEIC ACID REAGENT COMPOSED OF OLIGONUCLEOTIDES COVALENTLY ATTACHED TO POLYMER PARTICLES WHICH ARE ADHERED TO SUPPORT USING WATER INSOLUBLE ADHESIVE; LOW BACKGROUND JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) 1999-03-30 — — US disclosed
US-5380489-A Element and method for nucleic acid amplification and detection using adhered probes EASTMAN KODAK COMPANY (US) 1995-01-10 — — US disclosed
US-5374516-A Covalently attached to polymer particles of ethylenically unsaturated monomers with reactive alkylsulfonyl or halogen groups; detecting hormones, drugs, steroids in urine, blood, saliva EASTMAN KODAK COMPANY (US) 1994-12-20 — — US disclosed
EP-0347137-B1 Microporous article having a stabilized specific binding reagent, a method for its use and a diagnostic test kit EASTMAN KODAK CO (US) 1994-07-27 — — EP disclosed
US-5330891-A Method for detection of a nucleic acid using particulate reagent having polyoxyalkylene side chains EASTMAN KODAK COMPANY (US) 1994-07-19 — — US disclosed
US-5284752-A Methods of preparing a polymeric latex composition and water-insoluble biological reagent EASTMAN KODAK COMPANY (US) 1994-02-08 — — US disclosed
US-5268299-A Mixture of protein or carbohydrate and nonionic polyoxyethylene surfactant EASTMAN KODAK COMPANY (US) 1993-12-07 — — US disclosed
US-5234841-A Methods of preparing a polymeric latex composition and water-insoluble biological reagent EASTMAN KODAK COMPANY (US) 1993-08-10 — — US disclosed
US-5200315-A Nonporous particle is coated with copolymer of ethylene unsaturated reacted group, acrylic group with alkylene oxide branching and oleophilic addition monomers bonded to biological active substance; water insoluble; detection EASTMAN KODAK COMPANY (US) 1993-04-06 — — US disclosed
US-5086143-A COPOLYMERS CONTAINING POLYOXYALKYLENE SIDE CHAINS EASTMAN KODAK COMPANY (US) 1992-02-04 — — US disclosed
EP-0468584-A2 Copolymers containing polyoxyalkylene side chains Johnson & Johnson Clinical Diagnostics, Inc. (US) 1992-01-29 — — EP disclosed
EP-0468585-A2 Biologically active reagent, analytical element and methods for use of the reagent Johnson & Johnson Clinical Diagnostics, Inc. (US) 1992-01-29 — — EP disclosed
US-5077198-A DIAGNOSTIC KIT AND METHOD FOR RAPID DETECTION OF ANTIBODIES EASTMAN KODAK COMPANY (US) 1991-12-31 — — US disclosed
US-5053443-A Methods of preparing a polymeric latex composition and water-insoluble biological reagent EASTMAN KODAK COMPANY (US) 1991-10-01 — — US disclosed
EP-0430371-A2 Dry immunoassay analytical element comprising monodispersed beads Johnson & Johnson Clinical Diagnostics, Inc. (US) 1991-06-05 — — EP disclosed
US-4997772-A Shell-core polymers EASTMAN KODAK COMPANY (US) 1991-03-05 — — US disclosed
EP-0409977-A1 METHOD AND KIT FOR DETERMINATION OF HERPES SIMPLEX VIRAL ANTIGEN BY DIRECT BINDING TO POLYMERIC PARTICLES EASTMAN KODAK COMPANY (US) 1991-01-30 — — EP disclosed
WO-1990009593-A1 METHOD AND KIT FOR DETERMINATION OF HERPES SIMPLEX VIRAL ANTIGEN BY DIRECT BINDING TO POLYMERIC PARTICLES EASTMAN KODAK COMPANY (US) 1990-08-23 — — WO disclosed
Send feedback