Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 2/20 | 0.36 |
| ▸ | CHAT | P28329 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8438631 | 0.82 | CDK2 (0.44) | CYP2C9SMN1; SMN2CYP2D6CYP3A4MEN1 | |
| SCHEMBL7969857 | 0.81 | NFE2L2 (0.49) | CHRM5NFE2L2CYP1A2CYP2C9SMN1; SMN2 | |
| SCHEMBL7971923 | 0.75 | CHRM5 (0.47) | CHRM5NFE2L2CYP1A2CYP2C9FBP1 | |
| SCHEMBL3300271 | 0.73 | CHRM5 (0.62) | CHRM5CYP1A2CYP2C9FBP1CHAT | |
| SCHEMBL28846909 | 0.72 | NFE2L2 (0.51) | CHRM5NFE2L2CYP1A2CYP2C9SMN1; SMN2 | |
| SCHEMBL8435518 | 0.70 | CYP1A1 (0.54) | CHRM5NFE2L2CYP1A2SMN1; SMN2CYP2D6 | |
| SCHEMBL16608879 | 0.70 | GRM4 (0.64) | CYP1A2CYP2C9SMN1; SMN2CYP2D6CYP3A4 | |
| SCHEMBL8438601 | 0.70 | CHRM5 (0.42) | CHRM5NFE2L2CYP1A2CYP2C9FBP1 | |
| SCHEMBL28846944 | 0.68 | CHRM5 (0.47) | CHRM5NFE2L2CYP1A2CYP2C9SMN1; SMN2 | |
| SCHEMBL5540093 | 0.68 | CHRM5 (0.43) | CHRM5CYP1A2CYP2C9FBP1CHAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968947-A | INSECTICIDES, ACARICIDES, NEMATOCIDES | ZENECA LIMITED (GB) | 1999-10-19 | — | — | US | disclosed |