Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.49 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | FBP1 | P09467 | 2/20 | 0.39 |
| ▸ | CHAT | P28329 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7970291 | 0.82 | TP53 (0.44) | NFE2L2CYP1A2CYP2C9SMN1; SMN2FBP1 | |
| SCHEMBL8436005 | 0.81 | CHRM5 (0.42) | NFE2L2CHRM5CYP1A2CYP2C9SMN1; SMN2 | |
| SCHEMBL7972007 | 0.78 | NFE2L2 (0.54) | NFE2L2CHRM5CYP1A2FBP1RELA | |
| SCHEMBL3300271 | 0.77 | CHRM5 (0.62) | CHRM5CYP1A2CYP2C9FBP1CHAT | |
| SCHEMBL7971834 | 0.77 | TLR4 (0.42) | NFE2L2SMN1; SMN2MAPTKMT2AMAOB | |
| SCHEMBL7971685 | 0.76 | ALDH1A1 (0.52) | NFE2L2CYP1A2SMN1; SMN2FBP1MEN1 | |
| SCHEMBL7969643 | 0.76 | NFE2L2 (0.38) | NFE2L2SMN1; SMN2MAPT | |
| SCHEMBL7969371 | 0.75 | NPC1 (0.45) | NFE2L2CYP1A2SMN1; SMN2GRM5MEN1 | |
| SCHEMBL28846909 | 0.73 | NFE2L2 (0.51) | NFE2L2CHRM5CYP1A2CYP2C9SMN1; SMN2 | |
| SCHEMBL7971462 | 0.73 | NFE2L2 (0.39) | NFE2L2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001017965-A2 | CYANOPIPERIDINES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2001-03-15 | — | — | WO | disclosed |