Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | ACHE | P22303 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | FPR1 | P21462 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
| ▸ | CACNB4 | O00305 | 2/20 | 0.32 |
| ▸ | CACNA1A | O00555 | 2/20 | 0.32 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.32 |
| ▸ | CACNG3 | O60359 | 2/20 | 0.32 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.32 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.32 |
| ▸ | CACNB3 | P54284 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7501896 | 0.71 | L3MBTL1 (0.51) | KMT2ATP53HPGDSMN1; SMN2MAPT | |
| SCHEMBL7502555 | 0.67 | KDM4E (0.42) | KMT2ATP53HPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL7501517 | 0.66 | TP53 (0.52) | KMT2ATP53POLB | |
| SCHEMBL6075338 | 0.63 | TP53 (0.49) | KMT2ATP53ACHEHTTHPGD | |
| SCHEMBL6075340 | 0.63 | TP53 (0.48) | KMT2ATP53ACHEHTTHPGD | |
| SCHEMBL7495437 | 0.61 | POLB (0.55) | SMN1; SMN2POLB | |
| SCHEMBL6075899 | 0.61 | TP53 (0.40) | KMT2ATP53ACHEHTTSMN1; SMN2 | |
| SCHEMBL6076557 | 0.61 | KMT2A (0.43) | KMT2ATP53HTTHPGDSMN1; SMN2 | |
| SCHEMBL6076552 | 0.61 | KMT2A (0.43) | KMT2ATP53HTTHPGDSMN1; SMN2 | |
| SCHEMBL14529283 | 0.60 | BCHE (0.50) | TP53ACHENPC1BCHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5972946-A | NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1999-10-26 | — | — | US | disclosed |