Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7495188 | 0.88 | POLB (0.54) | PDE4BPOLB | |
| SCHEMBL7501896 | 0.79 | L3MBTL1 (0.51) | TP53KMT2APOLB | |
| SCHEMBL4807895 | 0.76 | GABRA1 (0.54) | — | |
| SCHEMBL6075338 | 0.74 | TP53 (0.49) | TP53KMT2A | |
| SCHEMBL6075340 | 0.73 | TP53 (0.48) | TP53KMT2APOLB | |
| SCHEMBL17313512 | 0.71 | PDE4B (0.82) | PDE4BPDE4D | |
| SCHEMBL14529283 | 0.71 | BCHE (0.50) | TP53 | |
| SCHEMBL4809314 | 0.71 | TP53 (0.46) | TP53KMT2APOLB | |
| SCHEMBL7500916 | 0.71 | POLB (0.43) | TP53PDE4BPDE4DPOLB | |
| SCHEMBL5734234 | 0.70 | TP53 (0.45) | TP53KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0826673-B1 | ACETAMIDE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL COMPOSITION CONTAINING THE SAME | DAINIPPON PHARMACEUTICAL CO (JP) | 2002-11-20 | — | — | EP | disclosed |
| US-5972946-A | NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1999-10-26 | — | — | US | disclosed |
| EP-0826673-A1 | ACETAMIDE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL COMPOSITION CONTAINING THE SAME | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1998-03-04 | — | — | EP | disclosed |