⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL179916 | 1.00 | — | — | |
| SCHEMBL501708 | 1.00 | — | — | |
| SCHEMBL8861236 | 0.96 | — | — | |
| Alcohol SCHEMBL10597860 | 0.89 | — | — | |
| Trimethylammonium SCHEMBL16632667 | 0.87 | TRPA1 (0.30) | — | |
| Trimethylammonium SCHEMBL16632668 | 0.87 | TRPA1 (0.30) | — | |
| Butadiene SCHEMBL8861158 | 0.87 | — | — | |
| Butadiene SCHEMBL8861155 | 0.87 | — | — | |
| SCHEMBL9735986 | 0.77 | ALDH1A1 (0.34) | — | |
| SCHEMBL38736 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2978318-A1 | METHODS OF CONTROLLING NEONICOTINOID RESISTANT PESTS | Syngenta Participations AG (CH) | 2016-02-03 | — | — | EP | disclosed |
| EP-2978316-A1 | METHODS OF CONTROLLING NEONICOTINOID RESISTANT PESTS | Syngenta Participations AG (CH) | 2016-02-03 | — | — | EP | disclosed |
| WO-2014154487-A1 | METHODS OF CONTROLLING NEONICOTINOID RESISTANT PESTS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-10-02 | — | — | WO | disclosed |
| WO-2014154488-A1 | METHODS OF CONTROLLING NEONICOTINOID RESISTANT PESTS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-10-02 | — | — | WO | disclosed |
| US-7786122-B2 | α-(N-sulfonamido)acetamide derivatives as β-amyloid inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-08-31 | — | — | US | disclosed |
| US-20080085894-A1 | ALPHA-(N-SULFONAMIDO)ACETAMIDE DERIVATIVES AS BETA-AMYLOID INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2008-04-10 | — | — | US | disclosed |
| US-7300936-B2 | α-(N-sulfonamido)acetamide derivatives as β-amyloid inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-11-27 | — | — | US | disclosed |
| US-5140030-A | Azido intermediates; carbapenicillin antibiotics | MERCK (US) | 1992-08-18 | — | — | US | disclosed |
| US-4892869-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1990-01-09 | — | — | US | disclosed |
| US-4833167-A | ANTIBIOTICS, BACTERICIDES | MERCK & CO., INC. (US) | 1989-05-23 | — | — | US | disclosed |
| US-4783453-A | 2-aza-substituted 1-carbadethiapen-2-em-3-carboxylic acids | MERCK & CO., INC. (US) | 1988-11-08 | — | — | US | disclosed |
| US-4782051-A | 2-aza-substituted 1-carbadethiapen-2-em-3 carboxylic acids | MERCK & CO., INC. (US) | 1988-11-01 | — | — | US | disclosed |
| US-4665026-A | Enzymatic synthesis of (S)3-hydroxy-3-methylglutaryl coenzyme A | REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE 2199 ADDISON ST., BERKELEY, CA. 94720 A CA CORP. | 1987-05-12 | — | — | US | disclosed |
| EP-0208889-A1 | 2-Aza-substituted 1-carbadethiapen-2-EM-3-carboxylic acids | MERCK & CO. INC. (US) | 1987-01-21 | — | — | EP | disclosed |
| US-4026909-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1977-05-31 | — | — | US | disclosed |