SCHEMBL8436272

SCHEMBL8436272

CCOC(=O)N1CC=CCN1C(=O)OCC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.42
LPO P22079 4/20 0.41
LMNA P02545 3/20 0.41
CYP1A2 P05177 1/20 0.41
TSHR P16473 1/20 0.41
HSD17B10 Q99714 1/20 0.40
POLB P06746 2/20 0.39
HTT P42858 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
GAA P10253 3/20 0.39
ALOX15 P16050 1/20 0.39
MGAM O43451 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
SOAT1 P35610 1/20 0.39
MAPT P10636 2/20 0.38
ABL1 P00519 1/20 0.38
RIN1 Q13671 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
RECQL P46063 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31503973 0.81 TSHR (0.50) ALDH1A1LMNATSHRPOLBHTT
SCHEMBL7778467 0.78 TSHR (0.47) ALDH1A1LMNATSHRHSD17B10POLB
SCHEMBL7394679 0.73 DPP4 (0.49) ALDH1A1LMNATSHRPOLBHTT
SCHEMBL4283831 0.71
SCHEMBL7779646 0.71 TSHR (0.41) ALDH1A1LMNATSHRHSD17B10POLB
SCHEMBL6192244 0.70 TSHR (0.33) ALDH1A1LPOLMNACYP1A2TSHR
SCHEMBL2914776 0.70 KMT2A (0.54) ALDH1A1LMNASMN1; SMN2GAATDP1
SCHEMBL2927542 0.70 TSHR (0.37) ALDH1A1LMNATSHRPOLBHTT
SCHEMBL3209999 0.70 TSHR (0.41) ALDH1A1LMNACYP1A2TSHRHSD17B10
SCHEMBL13484645 0.70 TSHR (0.41) ALDH1A1LMNACYP1A2TSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117362266-A Force-sensitive acetal monomer containing ladder alkene structure and degradable thermosetting polydicyclopentadiene material 安徽建筑大学 2024-01-09 CN disclosed
CN-102791133-B Fungicidal hetercyclic compounds E. I. DU PONT DE NEMOURS AND CO. (US) 2015-09-23 CN disclosed
US-5874382-A Cyclic sulfonamide herbicides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1999-02-23 US disclosed
US-5750471-A PREEMERGENCE, POSTEMERGENCE HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1998-05-12 US disclosed
EP-0765310-A1 HERBICIDAL BICYCLIC AND TRICYCLIC IMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-04-02 EP disclosed
WO-1995027698-A1 HERBICIDAL BICYCLIC AND TRICYCLIC IMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1995-10-19 WO disclosed
EP-0263299-B1 BENZOXAZINES NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1990-11-07 EP disclosed
US-4906281-A Herbicidal 9-arylimino-8-thia-1,6-diazabicyclo [4.3.0]nonane-7-ones (and thiones) FMC CORPORATION (US) 1990-03-06 US disclosed
EP-0263299-A1 Benzoxazines NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1988-04-13 EP disclosed
US-4128425-A PYRAZOLIDINONE DERIVATIVES POLAROID CORPORATION (US) 1978-12-05 US disclosed