Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7778467 | 0.91 | TSHR (0.47) | TSHRALDH1A1POLBHTTSMN1; SMN2 | |
| SCHEMBL11190071 | 0.82 | ALDH1A1 (0.43) | TSHRALDH1A1POLBHTTSMN1; SMN2 | |
| SCHEMBL10027108 | 0.80 | TSHR (0.39) | TSHRALDH1A1POLBHTTSMN1; SMN2 | |
| SCHEMBL11189598 | 0.79 | ALDH1A1 (0.41) | TSHRALDH1A1POLBHTTSMN1; SMN2 | |
| SCHEMBL7778464 | 0.76 | ALDH1A1 (0.38) | ALDH1A1POLBHTTSMN1; SMN2ATM | |
| SCHEMBL10309528 | 0.75 | TSHR (0.38) | TSHRALDH1A1POLBHTTSMN1; SMN2 | |
| SCHEMBL9470186 | 0.75 | CTSK (0.65) | TSHRALDH1A1POLBHTTSMN1; SMN2 | |
| SCHEMBL8612756 | 0.74 | ALDH1A1 (0.43) | ALDH1A1POLBHTTSMN1; SMN2ATM | |
| SCHEMBL13523486 | 0.73 | CTSK (0.59) | ALDH1A1SMN1; SMN2CTSKHSD17B10MAPT | |
| SCHEMBL2223429 | 0.73 | TSHR (0.63) | TSHRALDH1A1POLBHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0693482-B1 | PROCESS FOR PRODUCING HEXAHYDROPYRIDAZINE AND HEXAHYDROPYRIDAZINE-1,2-DICARBOXYLATE DERIVATIVE | IHARA CHEMICAL IND CO (JP) | 2001-09-12 | — | — | EP | disclosed |
| EP-0693482-A1 | PROCESS FOR PRODUCING HEXAHYDROPYRIDAZINE AND HEXAHYDROPYRIDAZINE-1,2-DICARBOXYLATE DERIVATIVE | IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) | 1996-01-24 | — | — | EP | disclosed |