Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 6/20 | 0.57 |
| ▸ | AGTR2 | P50052 | 6/20 | 0.57 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8434713 | 0.83 | AGTR1 (0.52) | AGTR1AGTR2 | |
| SCHEMBL8434715 | 0.82 | AGTR1 (0.50) | AGTR1AGTR2TLR7 | |
| SCHEMBL9030291 | 0.81 | AGTR1 (0.57) | AGTR1AGTR2 | |
| SCHEMBL8434651 | 0.81 | AGTR1 (0.49) | AGTR1AGTR2TLR7 | |
| SCHEMBL8438879 | 0.76 | AGTR1 (0.68) | AGTR1AGTR2 | |
| Water SCHEMBL8433835 | 0.75 | AGTR1 (0.67) | AGTR1AGTR2 | |
| SCHEMBL251 | 0.73 | AGTR1 (1.00) | AGTR1AGTR2 | |
| SCHEMBL345 | 0.73 | AGTR1 (0.75) | AGTR1AGTR2 | |
| SCHEMBL159 | 0.72 | AGTR1 (0.81) | AGTR1AGTR2 | |
| SCHEMBL8434404 | 0.71 | TLR7 (0.52) | AGTR1AGTR2TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929249-A | ANGIOTENSIN II RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-07-27 | — | — | US | claimed |
| EP-0653937-A4 | CHEMICAL COMPOUNDS. | SMITHKLINE BEECHAM CORP (US) | 1996-07-31 | — | — | EP | claimed |
| EP-0653937-A1 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-05-24 | — | — | EP | claimed |
| WO-1994000120-A1 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-01-06 | — | — | WO | claimed |
| US-5929249-A | ANGIOTENSIN II RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-07-27 | — | — | US | disclosed |
| US-5728842-A | ANGIOTENSIN II RECEPTOR ANTAGONIST | SMITHKLINE BEECHAM CORPORATION (US) | 1998-03-17 | — | — | US | disclosed |
| EP-0653937-A4 | CHEMICAL COMPOUNDS. | SMITHKLINE BEECHAM CORP (US) | 1996-07-31 | — | — | EP | disclosed |
| EP-0653937-A1 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-05-24 | — | — | EP | disclosed |
| WO-1994000120-A1 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-01-06 | — | — | WO | disclosed |