Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.65 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.65 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CTSL | P07711 | 6/20 | 0.54 |
| ▸ | FNTA | P49354 | 2/20 | 0.52 |
| ▸ | FNTB | P49356 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | TGM2 | P21980 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8436567 | 1.00 | HDAC1 (0.65) | HDAC1HDAC2CA1CTSLFNTA | |
| SCHEMBL27857345 | 0.91 | HDAC1 (0.55) | HDAC1HDAC2CA1CTSLFNTA | |
| SCHEMBL8435352 | 0.86 | HDAC1 (0.63) | HDAC1HDAC2CTSLTGM2 | |
| SCHEMBL8435348 | 0.86 | HDAC1 (0.63) | HDAC1HDAC2CTSLTGM2 | |
| SCHEMBL8433969 | 0.84 | CTSL (0.62) | HDAC1HDAC2CTSLTGM2 | |
| SCHEMBL8433892 | 0.84 | CTSL (0.62) | HDAC1HDAC2CTSLTGM2 | |
| SCHEMBL8436808 | 0.84 | CTSL (0.62) | HDAC1HDAC2CTSLTGM2 | |
| SCHEMBL8432468 | 0.84 | CTSL (0.65) | HDAC1HDAC2CTSL | |
| SCHEMBL8432473 | 0.84 | CTSL (0.65) | HDAC1HDAC2CTSL | |
| SCHEMBL11556459 | 0.83 | HDAC1 (0.57) | HDAC1HDAC2CTSLTGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5885816-A | OPTICALLY RESOLVING A RACEMIC MIXTURE OF AMINO ACID DERIVATIVES, COMPRISING USING A NONSPECIFIC CATALYTIC ANTIBODY WHICH ENANTIOSELECTIVELY HYDROLIZES VARIOUS AMINO ACID ESTER DERIVATIVES | PROTEIN ENGINEERING RESEARCH INSTITUTE (JP) | 1999-03-23 | — | — | US | disclosed |
| EP-0765940-A1 | CATALYTIC ANTIBODY WHICH HYDROLYZES AMINO ACID ESTER DERIVATIVE ENANTIOSELECTIVELY | PROTEIN ENGINEERING RESEARCH INSTITUTE (JP) | 1997-04-02 | — | — | EP | disclosed |